2LWR

Solution Structure of RING2 Domain from Parkin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004842	molecular_function	ubiquitin-protein transferase activity
A	0016567	biological_process	protein ubiquitination

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1

Chain	Residue
A	CYS436
A	CYS439
A	CYS454
A	CYS459

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 2

Chain	Residue
A	CYS464
A	CYS467
A	THR472
A	CYS475
A	HIS479

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	41
Details	ZN_FING: IBR-type => ECO:0000255

Chain	Residue	Details
A	SER432-ARG473

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site_id	SWS_FT_FI2
Number of Residues	31
Details	ZN_FING: RING-type 2; atypical => ECO:0000255|PROSITE-ProRule:PRU01221, ECO:0000269|PubMed:23770917

Chain	Residue	Details
A	CYS436-CYS467

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site_id	SWS_FT_FI3
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01221, ECO:0000269|PubMed:23770917, ECO:0000269|PubMed:32047033

Chain	Residue	Details
A	CYS449

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site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01221, ECO:0000269|PubMed:23770917, ECO:0007744|PDB:2LWR, ECO:0007744|PDB:2M48

Chain	Residue	Details
A	CYS436
A	CYS439
A	CYS454
A	CYS459
A	CYS464
A	CYS467
A	CYS475
A	HIS479

---