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2LQN

Solution structure of CRKL

Functional Information from GO Data
ChainGOidnamespacecontents
A0001558biological_processregulation of cell growth
A0001568biological_processblood vessel development
A0001655biological_processurogenital system development
A0001764biological_processneuron migration
A0001783biological_processB cell apoptotic process
A0001784molecular_functionphosphotyrosine residue binding
A0001933biological_processnegative regulation of protein phosphorylation
A0001934biological_processpositive regulation of protein phosphorylation
A0002685biological_processregulation of leukocyte migration
A0003151biological_processoutflow tract morphogenesis
A0003723molecular_functionRNA binding
A0005515molecular_functionprotein binding
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006629biological_processlipid metabolic process
A0007167biological_processenzyme-linked receptor protein signaling pathway
A0007254biological_processJNK cascade
A0007265biological_processRas protein signal transduction
A0007283biological_processspermatogenesis
A0007338biological_processsingle fertilization
A0007389biological_processpattern specification process
A0007507biological_processheart development
A0008284biological_processpositive regulation of cell population proliferation
A0008543biological_processfibroblast growth factor receptor signaling pathway
A0008584biological_processmale gonad development
A0009887biological_processanimal organ morphogenesis
A0009952biological_processanterior/posterior pattern specification
A0010468biological_processregulation of gene expression
A0010629biological_processnegative regulation of gene expression
A0016358biological_processdendrite development
A0016477biological_processcell migration
A0021766biological_processhippocampus development
A0021987biological_processcerebral cortex development
A0030010biological_processestablishment of cell polarity
A0030971molecular_functionreceptor tyrosine kinase binding
A0031594cellular_componentneuromuscular junction
A0032991cellular_componentprotein-containing complex
A0033628biological_processregulation of cell adhesion mediated by integrin
A0035022biological_processpositive regulation of Rac protein signal transduction
A0035556biological_processintracellular signal transduction
A0035591molecular_functionsignaling adaptor activity
A0035685biological_processhelper T cell diapedesis
A0038026biological_processreelin-mediated signaling pathway
A0042802molecular_functionidentical protein binding
A0043410biological_processpositive regulation of MAPK cascade
A0045202cellular_componentsynapse
A0045296molecular_functioncadherin binding
A0048384biological_processretinoic acid receptor signaling pathway
A0048538biological_processthymus development
A0050773biological_processregulation of dendrite development
A0050852biological_processT cell receptor signaling pathway
A0060017biological_processparathyroid gland development
A0060326biological_processcell chemotaxis
A0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
A0070374biological_processpositive regulation of ERK1 and ERK2 cascade
A0071466biological_processcellular response to xenobiotic stimulus
A0071560biological_processcellular response to transforming growth factor beta stimulus
A0071774biological_processresponse to fibroblast growth factor
A0086100biological_processendothelin receptor signaling pathway
A0095500biological_processacetylcholine receptor signaling pathway
A0098698biological_processpostsynaptic specialization assembly
A0098749biological_processcerebellar neuron development
A0098761biological_processcellular response to interleukin-7
A0098890cellular_componentextrinsic component of postsynaptic membrane
A0160093biological_processchordate pharynx development
A1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
A1902531biological_processregulation of intracellular signal transduction
A1903977biological_processpositive regulation of glial cell migration
A1904393biological_processregulation of skeletal muscle acetylcholine-gated channel clustering
A1904395biological_processpositive regulation of skeletal muscle acetylcholine-gated channel clustering
A1904888biological_processcranial skeletal system development
A2000145biological_processregulation of cell motility
A2000404biological_processregulation of T cell migration
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:19690332
ChainResidueDetails
ATYR127

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:15592455
ChainResidueDetails
ATYR207

219140

PDB entries from 2024-05-01

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