2LMD

Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	58
Details	Domain: {"description":"Prospero-type homeo","evidences":[{"source":"PROSITE-ProRule","id":"PRU01162","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	99
Details	Domain: {"description":"Prospero","evidences":[{"source":"PROSITE-ProRule","id":"PRU01162","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	158
Details	Region: {"description":"Homeo-Prospero","evidences":[{"source":"PROSITE-ProRule","id":"PRU01162","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	6
Details	Region: {"description":"Essential for nuclear localization, interaction with RORG, repression of RORG transcriptional activator activity","evidences":[{"source":"UniProtKB","id":"P48437","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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