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2LFB

HOMEODOMAIN FROM RAT LIVER LFB1/HNF1 TRANSCRIPTION FACTOR, NMR, 20 STRUCTURES

Functional Information from GO Data
ChainGOidnamespacecontents
A0001889biological_processliver development
A0003677molecular_functionDNA binding
A0006357biological_processregulation of transcription by RNA polymerase II
A0030073biological_processinsulin secretion
A0031016biological_processpancreas development
Functional Information from PDB Data
site_idS1
Number of Residues2
DetailsDNA-BINDING.
ChainResidue
AASN76
ALYS83

Functional Information from PROSITE/UniProt
site_idPS00027
Number of Residues24
DetailsHOMEOBOX_1 'Homeobox' domain signature. GLgsNlVTevRVYNWFaNrrkeeA
ChainResidueDetails
AGLY63-ALA86

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues80
DetailsDNA_BIND: Homeobox; HNF1-type => ECO:0000255|PROSITE-ProRule:PRU00108
ChainResidueDetails
AGLY9-HIS89

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903
ChainResidueDetails
ASER57

227111

PDB entries from 2024-11-06

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