2LFB

HOMEODOMAIN FROM RAT LIVER LFB1/HNF1 TRANSCRIPTION FACTOR, NMR, 20 STRUCTURES

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001889	biological_process	liver development
A	0003677	molecular_function	DNA binding
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0030073	biological_process	insulin secretion
A	0031016	biological_process	pancreas development

Functional Information from PDB Data

site_id	S1
Number of Residues	2
Details	DNA-BINDING.

Chain	Residue
A	ASN76
A	LYS83

---

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. GLgsNlVTevRVYNWFaNrrkeeA

Chain	Residue	Details
A	GLY63-ALA86

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	DNA_BIND: Homeobox; HNF1-type => ECO:0000255|PROSITE-ProRule:PRU00108

Chain	Residue	Details
A	GLY9-HIS89

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903

Chain	Residue	Details
A	SER57

---