2LDU

Solution NMR Structure of Heat shock factor protein 1 DNA binding domain from homo sapiens, Northeast Structural Genomics Consortium Target HR3023C

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PROSITE/UniProt

site_id	PS00434
Number of Residues	25
Details	HSF_DOMAIN HSF-type DNA-binding domain signature. LpkyFKHnNmASFVRQLNmYgFRKV

Chain	Residue	Details
A	LEU59-VAL83

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:19229036, ECO:0000269|PubMed:24581496

Chain	Residue	Details
A	LYS82

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000269|PubMed:24581496

Chain	Residue	Details
A	LYS93

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:24581496, ECO:0000269|PubMed:26754925

Chain	Residue	Details
A	LYS120

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine; by MAPKAPK2 => ECO:0000269|PubMed:15760475, ECO:0000269|PubMed:16278218

Chain	Residue	Details
A	SER123

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site_id	SWS_FT_FI5
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733

Chain	Residue	Details
A	LYS93

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