2L8R
Solution structure of human protein C6orf130 in complex with ADP-ribose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001883 | molecular_function | purine nucleoside binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005694 | cellular_component | chromosome |
| A | 0005730 | cellular_component | nucleolus |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042278 | biological_process | purine nucleoside metabolic process |
| A | 0051725 | biological_process | protein de-ADP-ribosylation |
| A | 0061463 | molecular_function | O-acetyl-ADP-ribose deacetylase activity |
| A | 0090734 | cellular_component | site of DNA damage |
| A | 0140291 | biological_process | peptidyl-glutamate ADP-deribosylation |
| A | 0140293 | molecular_function | ADP-ribosylglutamate hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE APR A 186 |
| Chain | Residue |
| A | ASP20 |
| A | THR83 |
| A | PRO91 |
| A | PRO118 |
| A | ARG119 |
| A | ILE120 |
| A | GLY123 |
| A | LEU124 |
| A | ASP125 |
| A | LEU152 |
| A | LEU21 |
| A | PHE22 |
| A | CYS33 |
| A | ILE34 |
| A | SER35 |
| A | ARG39 |
| A | ILE44 |
| A | LEU47 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:23481255 |
| Chain | Residue | Details |
| A | LYS84 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000269|PubMed:21849506, ECO:0000269|PubMed:23481255 |
| Chain | Residue | Details |
| A | ASP125 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21849506 |
| Chain | Residue | Details |
| A | LEU21 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21849506, ECO:0000269|PubMed:23481255 |
| Chain | Residue | Details |
| A | ARG119 | |
| A | LEU152 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692 |
| Chain | Residue | Details |
| A | SER4 |
