2L8R
Solution structure of human protein C6orf130 in complex with ADP-ribose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001883 | molecular_function | purine nucleoside binding |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005694 | cellular_component | chromosome |
| A | 0005730 | cellular_component | nucleolus |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042278 | biological_process | purine nucleoside metabolic process |
| A | 0047407 | molecular_function | ADP-ribosyl-[dinitrogen reductase] hydrolase activity |
| A | 0051725 | biological_process | protein de-ADP-ribosylation |
| A | 0061463 | molecular_function | O-acetyl-ADP-ribose deacetylase activity |
| A | 0090734 | cellular_component | site of DNA damage |
| A | 0140291 | biological_process | peptidyl-glutamate ADP-deribosylation |
| A | 0140293 | molecular_function | ADP-ribosylglutamate hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE APR A 186 |
| Chain | Residue |
| A | ASP20 |
| A | THR83 |
| A | PRO91 |
| A | PRO118 |
| A | ARG119 |
| A | ILE120 |
| A | GLY123 |
| A | LEU124 |
| A | ASP125 |
| A | LEU152 |
| A | LEU21 |
| A | PHE22 |
| A | CYS33 |
| A | ILE34 |
| A | SER35 |
| A | ARG39 |
| A | ILE44 |
| A | LEU47 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"23481255","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"21849506","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23481255","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21849506","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21849506","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23481255","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
