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2L4S

Promiscuous Binding at the Crossroads of Numerous Cancer Pathways: Insight from the Binding of GIP with Glutaminase L

Functional Information from GO Data
ChainGOidnamespacecontents
A0001650cellular_componentfibrillar center
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0007266biological_processRho protein signal transduction
A0008013molecular_functionbeta-catenin binding
A0008285biological_processnegative regulation of cell population proliferation
A0015629cellular_componentactin cytoskeleton
A0016055biological_processWnt signaling pathway
A0030178biological_processnegative regulation of Wnt signaling pathway
A0043231cellular_componentintracellular membrane-bounded organelle
A0070062cellular_componentextracellular exosome
A0090630biological_processactivation of GTPase activity
A2000009biological_processnegative regulation of protein localization to cell surface
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378
ChainResidueDetails
ASER2

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER61

222036

PDB entries from 2024-07-03

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