2L2E

Solution NMR structure of myristoylated NCS1p in apo form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0008047	molecular_function	enzyme activator activity
A	0009966	biological_process	regulation of signal transduction
A	0016020	cellular_component	membrane
A	0019722	biological_process	calcium-mediated signaling
A	0030435	biological_process	sporulation resulting in formation of a cellular spore
A	0032588	cellular_component	trans-Golgi network membrane
A	0046854	biological_process	phosphatidylinositol phosphate biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0098744	molecular_function	1-phosphatidylinositol 4-kinase activator activity
A	1905949	biological_process	negative regulation of calcium ion import across plasma membrane

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DADKNGYIDfkEF

Chain	Residue	Details
A	ASP73-PHE85
A	ASP109-MET121
A	ASP157-PHE169

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448

Chain	Residue	Details
A	ASP73
A	ASP157
A	ASN159
A	ASP161
A	GLN163
A	GLU168
A	ASP75
A	ASN77
A	TYR79
A	GLU84
A	ASP109
A	ASP111
A	ASN113
A	GLU120

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	LIPID: N-myristoyl glycine => ECO:0000269|PubMed:14722091

Chain	Residue	Details
A	GLY2

---