2L0R
Conformational Dynamics of the Anthrax Lethal Factor Catalytic Center
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008237 | molecular_function | metallopeptidase activity |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. GFIHEFGHAV |
Chain | Residue | Details |
A | GLY13-VAL22 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU01339, ECO:0000269|PubMed:19651869, ECO:0000269|PubMed:9573135 |
Chain | Residue | Details |
A | GLU17 |
Chain | Residue | Details |
A | HIS16 | |
A | HIS20 | |
A | GLU65 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01339 |
Chain | Residue | Details |
A | TYR58 |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 641 |
Chain | Residue | Details |
A | HIS16 | metal ligand |
A | GLU17 | proton acceptor, proton donor |
A | HIS20 | metal ligand |
A | TYR58 | electrostatic stabiliser |
A | GLU65 | metal ligand |