2KWO

Solution structure of the double PHD (plant homeodomain) fingers of human transcriptional protein DPF3b bound to a histone H4 peptide containing N-terminal acetylation at Serine 1

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 501

Chain	Residue
A	CYS262
A	CYS265
A	ASN272
A	HIS292
A	CYS295

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 601

Chain	Residue
A	CYS284
A	CYS287
A	CYS313
A	CYS316

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 701

Chain	Residue
A	CYS334
A	CYS337
A	ARG339
A	CYS360
A	CYS363

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 801

Chain	Residue
A	CYS319
A	CYS322
A	HIS342
A	CYS345

---

Functional Information from PROSITE/UniProt

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
B	GLY14-HIS18

---

site_id	PS01359
Number of Residues	80
Details	ZF_PHD_1 Zinc finger PHD-type signature. CadCgrsghptclqftlnmteavktykwqcieckscilcgtsenddql.LfCdd..Cdrg.YHmyClnppvaeppegs.................................WsChlC

Chain	Residue	Details
A	CYS284-CYS363

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	DNA_BIND:

Chain	Residue	Details
B	LYS16-LYS20

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:17967882

Chain	Residue	Details
B	SAC1

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Symmetric dimethylarginine; by PRMT5 and PRMT7; alternate => ECO:0000250|UniProtKB:P62806

Chain	Residue	Details
B	ARG3

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-lactoyllysine; alternate => ECO:0000269|PubMed:31645732

Chain	Residue	Details
B	LYS5

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: N6-propionyllysine; alternate => ECO:0000269|PubMed:17267393

Chain	Residue	Details
B	LYS8
B	LYS16

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435

Chain	Residue	Details
B	LYS12

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:12086618, ECO:0000269|PubMed:15964846, ECO:0000269|PubMed:17967882, ECO:0000269|PubMed:27338793

Chain	Residue	Details
B	LYS20

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447

Chain	Residue	Details
B	LYS12

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733

Chain	Residue	Details
B	LYS20

---