2KV1
Insights into Function, Catalytic Mechanism and Fold Evolution of Mouse Selenoprotein Methionine Sulfoxide Reductase B1 through Structural Analysis
Replaces: 2KAOFunctional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002376 | biological_process | immune system process |
| A | 0003779 | molecular_function | actin binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0030041 | biological_process | actin filament polymerization |
| A | 0030091 | biological_process | protein repair |
| A | 0033743 | molecular_function | peptide-methionine (R)-S-oxide reductase activity |
| A | 0033745 | molecular_function | L-methionine-(R)-S-oxide reductase activity |
| A | 0045087 | biological_process | innate immune response |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 125 |
| Chain | Residue |
| A | CYS23 |
| A | CYS26 |
| A | CYS71 |
| A | CYS74 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 105 |
| Details | Domain: {"description":"MsrB","evidences":[{"source":"PROSITE-ProRule","id":"PRU01126","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU01126","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01126","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20605785","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2KV1","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Non-standard residue: {"description":"Selenocysteine","evidences":[{"source":"PubMed","id":"10567350","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
