2KV1

Insights into Function, Catalytic Mechanism and Fold Evolution of Mouse Selenoprotein Methionine Sulfoxide Reductase B1 through Structural Analysis

Replaces:  2KAO

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003779	molecular_function	actin binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005856	cellular_component	cytoskeleton
A	0008270	molecular_function	zinc ion binding
A	0015629	cellular_component	actin cytoskeleton
A	0016491	molecular_function	oxidoreductase activity
A	0030041	biological_process	actin filament polymerization
A	0030091	biological_process	protein repair
A	0033743	molecular_function	peptide-methionine (R)-S-oxide reductase activity
A	0033745	molecular_function	L-methionine-(R)-S-oxide reductase activity
A	0045087	biological_process	innate immune response
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 125

Chain	Residue
A	CYS23
A	CYS26
A	CYS71
A	CYS74

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU01126

Chain	Residue	Details
A	CYS95

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01126, ECO:0000269|PubMed:20605785, ECO:0000312|PDB:2KV1

Chain	Residue	Details
A	CYS23
A	CYS26
A	CYS71
A	CYS74

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