2KT2

Structure of NmerA, the N-terminal HMA domain of Tn501 Mercuric Reductase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS01047
Number of Residues	30
Details	HMA_1 Heavy-metal-associated domain. ItGMtCdSCaahVKeaLekvpgvqsal.VsY

Chain	Residue	Details
A	ILE6-TYR35

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00280

Chain	Residue	Details
A	CYS11
A	CYS14

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 277

Chain	Residue	Details
A	MET9	electrostatic stabiliser, increase nucleophilicity, steric role
A	CYS11	activator, covalently attached, electrostatic stabiliser, metal ligand, nucleofuge, nucleophile, proton acceptor, proton donor
A	CYS14	activator, covalently attached, electrofuge, electrophile, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, increase nucleophilicity, metal ligand, nucleofuge, nucleophile, proton acceptor, proton donor
A	TYR62	electrostatic stabiliser, hydrogen bond acceptor

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