2KMB

COMPLEX OF 3'-NEUAC-LEWIS-X WITH A SELECTIN-LIKE MUTANT OF MANNOSE-BINDING PROTEIN A

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0001867	biological_process	complement activation, lectin pathway
1	0005537	molecular_function	mannose binding
2	0001867	biological_process	complement activation, lectin pathway
2	0005537	molecular_function	mannose binding
3	0001867	biological_process	complement activation, lectin pathway
3	0005537	molecular_function	mannose binding

Functional Information from PDB Data

site_id	11
Number of Residues	7
Details	CA SITE 1, PROTOMER 1.

Chain	Residue
1	CA1
1	ASP161
1	GLU165
1	ASP188
1	GLU193
1	ASP194
2	HOH324

---

site_id	12
Number of Residues	7
Details	CA SITE 1, PROTOMER 2.

Chain	Residue
2	GLU165
2	ASP188
2	GLU193
2	ASP194
2	HOH262
2	CA1
2	ASP161

---

site_id	13
Number of Residues	7
Details	CA SITE 1, PROTOMER 3.

Chain	Residue
3	CA1
3	ASP161
3	GLU165
3	ASP188
3	GLU193
3	ASP194
3	HOH304

---

site_id	21
Number of Residues	7
Details	CA SITE 2, PROTOMER 1.

Chain	Residue
1	CA2
1	GLU185
1	ASN187
1	GLU193
1	ASN205
1	ASP206
2	HOH316

---

site_id	22
Number of Residues	7
Details	CA SITE 2, PROTOMER 2.

Chain	Residue
2	CA2
2	GLU185
2	ASN187
2	GLU193
2	ASN205
2	ASP206
2	HOH269

---

site_id	23
Number of Residues	8
Details	CA SITE 2, PROTOMER 3.

Chain	Residue
3	CA2
3	GLU185
3	ASN187
3	GLU193
3	ASN205
3	ASP206
3	HOH296
3	HOH297

---

site_id	31
Number of Residues	6
Details	CA SITE 3, PROTOMER 1.

Chain	Residue
1	CA3
1	GLU165
1	ASP194
2	HOH325
2	HOH331
2	HOH332

---

site_id	32
Number of Residues	4
Details	CA SITE 3, PROTOMER 2.

Chain	Residue
2	CA3
2	GLU165
2	ASP194
2	HOH263

---

site_id	33
Number of Residues	4
Details	CA SITE 3, PROTOMER 3.

Chain	Residue
3	CA3
3	GLU165
3	ASP194
1	HOH404

---

Functional Information from PROSITE/UniProt

site_id	PS00615
Number of Residues	23
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CVtivdngl.....WNDISCqkkkt.AVC

Chain	Residue	Details
1	CYS195-CYS217

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	285
Details	Domain: {"description":"C-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00040","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Region: {"description":"Calcium-dependent carbohydrate binding","evidences":[{"source":"PubMed","id":"11850428","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1436090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9033386","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11850428","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1436090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7704532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9033386","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AFA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AFB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BCH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BCJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RTM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2MSB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KMB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	15
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11850428","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1436090","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7704532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9033386","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KWZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KX1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RTM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2MSB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KMB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---