2KLH
NMR Structure of RCL in complex with GMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009159 | biological_process | deoxyribonucleoside monophosphate catabolic process |
| A | 0070694 | molecular_function | 5-hydroxymethyl-dUMP N-hydrolase activity |
| B | 0009159 | biological_process | deoxyribonucleoside monophosphate catabolic process |
| B | 0070694 | molecular_function | 5-hydroxymethyl-dUMP N-hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 5GP A 187 |
| Chain | Residue |
| A | TYR13 |
| A | ILE65 |
| A | GLN68 |
| A | ALA69 |
| A | TRP72 |
| A | GLY89 |
| A | GLU93 |
| B | SER117 |
| B | ALA118 |
| B | MET119 |
| A | CYS15 |
| A | GLY16 |
| A | SER17 |
| A | ILE18 |
| A | ARG19 |
| A | TYR28 |
| A | THR43 |
| A | HIS45 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 5GP B 187 |
| Chain | Residue |
| A | SER117 |
| A | ALA118 |
| A | MET119 |
| B | TYR13 |
| B | CYS15 |
| B | GLY16 |
| B | SER17 |
| B | ILE18 |
| B | ARG19 |
| B | TYR28 |
| B | THR43 |
| B | HIS45 |
| B | ILE65 |
| B | GLN68 |
| B | ALA69 |
| B | TRP72 |
| B | GLY89 |
| B | GLU93 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23385460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24260472","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25108359","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FYH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P5D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"23385460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24260472","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25108359","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FYH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FYK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KXN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P5D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O43598","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
