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2KK6

Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d

Functional Information from GO Data
ChainGOidnamespacecontents
A0004713molecular_functionprotein tyrosine kinase activity
A0005154molecular_functionepidermal growth factor receptor binding
A0008283biological_processcell population proliferation
A0030335biological_processpositive regulation of cell migration
A0031532biological_processactin cytoskeleton reorganization
A0042058biological_processregulation of epidermal growth factor receptor signaling pathway
A0051092biological_processpositive regulation of NF-kappaB transcription factor activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues90
DetailsDomain: {"description":"SH2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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