2KAD
Magic-Angle-Spinning Solid-State NMR Structure of Influenza A M2 Transmembrane Domain
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0015078 | molecular_function | proton transmembrane transporter activity |
A | 0033644 | cellular_component | host cell membrane |
A | 0055036 | cellular_component | virion membrane |
A | 1902600 | biological_process | proton transmembrane transport |
B | 0015078 | molecular_function | proton transmembrane transporter activity |
B | 0033644 | cellular_component | host cell membrane |
B | 0055036 | cellular_component | virion membrane |
B | 1902600 | biological_process | proton transmembrane transport |
C | 0015078 | molecular_function | proton transmembrane transporter activity |
C | 0033644 | cellular_component | host cell membrane |
C | 0055036 | cellular_component | virion membrane |
C | 1902600 | biological_process | proton transmembrane transport |
D | 0015078 | molecular_function | proton transmembrane transporter activity |
D | 0033644 | cellular_component | host cell membrane |
D | 0055036 | cellular_component | virion membrane |
D | 1902600 | biological_process | proton transmembrane transport |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE 308 A 1 |
Chain | Residue |
A | ALA30 |
A | SER31 |
A | GLY34 |
B | ALA30 |
B | SER31 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 80 |
Details | TRANSMEM: Helical; Signal-anchor for type III membrane protein => ECO:0000255|HAMAP-Rule:MF_04069 |
Chain | Residue | Details |
A | SER23-LEU43 | |
B | SER23-LEU43 | |
C | SER23-LEU43 | |
D | SER23-LEU43 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | SITE: Essential for channel activity, possibly by being protonated during channel activation, and by forming the channel gate and the selective filter => ECO:0000255|HAMAP-Rule:MF_04069 |
Chain | Residue | Details |
A | HIS37 | |
B | HIS37 | |
C | HIS37 | |
D | HIS37 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | SITE: Seems to be involved in pH gating => ECO:0000255|HAMAP-Rule:MF_04069 |
Chain | Residue | Details |
A | TRP41 | |
B | TRP41 | |
C | TRP41 | |
D | TRP41 |