2K9O
Solution structure of Vm24 synthetic scorpion toxin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0008200 | molecular_function | ion channel inhibitor activity |
| A | 0015459 | molecular_function | potassium channel regulator activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from PROSITE/UniProt
| site_id | PS01138 |
| Number of Residues | 22 |
| Details | SCORP_SHORT_TOXIN Scorpion short toxins signature. CppkCraqgckn..GKCMnrkCkC |
| Chain | Residue | Details |
| A | CYS12-CYS33 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Site: {"description":"Basic residue of the functional dyad"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Aromatic residue of the functional dyad"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Cysteine amide","evidences":[{"source":"PubMed","id":"22540187","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"patent","publicationDate":"10-MAR-2011","patentNumber":"US0059064","title":"Vm23 and Vm24, two scorpion peptides that block human T-lymphocyte potassium channels sub-type K(v)1.3 w/high selectivity and decrease the in vivo DTH responses in rats.","authors":["Possani L.D.","Gurrola G.B.","Salas-Castillo S.P.","Batista C.V.F.","Varga Z.","Panyi G.","Caspar R."]}}]} |
| Chain | Residue | Details |
