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2K8R

Solution structure of human acidic fibroblast growth factor in complex with anti-angiogenic drug inositol hexaphosphate (IP6)

Functional Information from GO Data
ChainGOidnamespacecontents
A0008083molecular_functiongrowth factor activity
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE IHP A 134
ChainResidue
ALYS105
ALYS111
APRO114
AARG115
ATYR118
AGLY119
ALYS121

Functional Information from PROSITE/UniProt
site_idPS00247
Number of Residues24
DetailsHBGF_FGF HBGF/FGF family signature. GlLyGsqtpne.EClFlErleenhY
ChainResidueDetails
AGLY64-TYR87

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:11069186, ECO:0000269|PubMed:9655399
ChainResidueDetails
AASN11

221716

PDB entries from 2024-06-26

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