2K1R

The solution NMR structure of the complex between MNK1 and HAH1 mediated by Cu(I)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0046872	molecular_function	metal ion binding
B	0005507	molecular_function	copper ion binding
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0006825	biological_process	copper ion transport
B	0006878	biological_process	intracellular copper ion homeostasis
B	0006979	biological_process	response to oxidative stress
B	0016530	molecular_function	metallochaperone activity
B	0016531	molecular_function	copper chaperone activity
B	0032767	molecular_function	copper-dependent protein binding
B	0046872	molecular_function	metal ion binding
B	1903136	molecular_function	cuprous ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU A 142

Chain	Residue
A	MET13
A	CYS15
A	ASN16
A	SER17

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Functional Information from PROSITE/UniProt

site_id	PS01047
Number of Residues	29
Details	HMA_1 Heavy-metal-associated domain. SvDMtCgGCaeaVSrvLnklggvkyd..IdL

Chain	Residue	Details
B	SER80-LEU108
A	VAL10-LEU39

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00280, ECO:0000269|PubMed:31283225, ECO:0007744|PDB:5T7L

Chain	Residue	Details
B	CYS85
B	CYS88

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
B	SER120
A	CYS18

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:O08997

Chain	Residue	Details
B	LYS133

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