2K1Q

NMR structure of hepatitis c virus ns3 serine protease complexed with the non-covalently bound phenethylamide inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity
A	0019087	biological_process	transformation of host cell by virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IBU B 187

Chain	Residue
A	ALA156
A	ALA157
A	CYS159
B	LEU189

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE OBF B 190

Chain	Residue
A	PHE154
A	SER42
A	SER133
A	LEU135
A	LYS136
A	SER139

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE3 B 191

Chain	Residue
A	THR38
A	THR40
A	GLN41
A	SER42
A	LYS136
A	SER139
B	GLU188

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 301

Chain	Residue
A	CYS97
A	THR98
A	CYS99
A	CYS145
A	PRO146
A	SER147

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