2JUT
alpha RgIA, a Novel Conotoxin that Blocks the alpha9-alpha10 nAChR
Functional Information from PROSITE/UniProt
| site_id | PS60014 |
| Number of Residues | 11 |
| Details | ALPHA_CONOTOXIN Alpha-conotoxin family signature. CCSdPRCR....YRC |
| Chain | Residue | Details |
| A | CYS2-CYS12 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | SITE: Key residue for potent inhibition of the rat CHRNA9-CHRNA10 nAChR => ECO:0000269|PubMed:18295795 |
| Chain | Residue | Details |
| A | ASP5 | |
| A | PRO6 | |
| A | ARG7 | |
| A | ARG9 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Binds to the Glu-221 of the rat nAChR CHRNA10 subunit => ECO:0000305|PubMed:25740413 |
| Chain | Residue | Details |
| A | ARG11 |
