2JUQ

alpha-RgIA, a Novel Conotoxin that Blocks the alpha9-alpha10 nAChR

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Peptide: {"description":"Alpha-conotoxin RgIA","featureId":"PRO_0000234830","evidences":[{"source":"PubMed","id":"16445293","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"18242183","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"18295795","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"18945902","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"21888386","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"22774872","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25008370","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25393758","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25740413","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Site: {"description":"Key residue for potent inhibition of the rat CHRNA9-CHRNA10 nAChR","evidences":[{"source":"PubMed","id":"18295795","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Binds to the Glu-221 of the rat nAChR CHRNA10 subunit","evidences":[{"source":"PubMed","id":"25740413","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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