2JU0

Structure of Yeast Frequenin bound to PdtIns 4-kinase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0005509	molecular_function	calcium ion binding
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0008047	molecular_function	enzyme activator activity
A	0009966	biological_process	regulation of signal transduction
A	0016020	cellular_component	membrane
A	0033101	cellular_component	cellular bud membrane
A	0046872	molecular_function	metal ion binding
A	0098744	molecular_function	1-phosphatidylinositol 4-kinase activator activity
B	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 500

Chain	Residue
A	PHE72
A	ASP73
A	LYS74
A	ASP75
A	ASN76
A	ASN77

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 501

Chain	Residue
A	ILE116
A	THR117
A	TYR108
A	ASP109
A	TYR115

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CA A 502

Chain	Residue
A	ASP157
A	ASN159

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DLNHDGYITfdEM

Chain	Residue	Details
A	ASP109-MET121
A	ASP157-PHE169

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Domain: {"description":"EF-hand 1","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	35
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	35
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	15
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---