Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 273 |
| Chain | Residue |
| A | ASP183 |
| A | GLY184 |
| A | ARG186 |
| A | THR188 |
| A | ASP206 |
| A | GLU209 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 274 |
| Chain | Residue |
| A | GLU197 |
| A | GLY198 |
| A | GLY200 |
| A | ASP202 |
| A | GLU164 |
| A | ALA165 |
| A | ASP166 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 275 |
| Chain | Residue |
| A | HIS176 |
| A | ASP178 |
| A | HIS191 |
| A | HIS204 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 276 |
| Chain | Residue |
| A | HIS226 |
| A | HIS230 |
| A | HIS236 |
| A | NGH277 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE NGH A 277 |
| Chain | Residue |
| A | GLY187 |
| A | THR188 |
| A | LEU189 |
| A | ALA190 |
| A | THR222 |
| A | HIS226 |
| A | GLU227 |
| A | HIS230 |
| A | HIS236 |
| A | TYR245 |
| A | PRO246 |
| A | THR247 |
| A | TYR248 |
| A | LYS249 |
| A | ZN276 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHEFGHAL |
| Chain | Residue | Details |
| A | VAL223-LEU232 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU227 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU164 | |
| A | HIS191 | |
| A | GLU197 | |
| A | GLY198 | |
| A | GLY200 | |
| A | ASP202 | |
| A | HIS204 | |
| A | ASP206 | |
| A | GLU209 | |
| A | HIS226 | |
| A | HIS230 | |
| A | ALA165 | |
| A | HIS236 | |
| A | ASP166 | |
| A | HIS176 | |
| A | ASP178 | |
| A | ASP183 | |
| A | GLY184 | |
| A | ARG186 | |
| A | THR188 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | GLU227 | |
| A | MET244 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hfs |
| Chain | Residue | Details |
| A | GLU227 | |
