Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| B | 0004386 | molecular_function | helicase activity |
| B | 0005524 | molecular_function | ATP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP A1619 |
| Chain | Residue |
| A | GLY196 |
| A | ARG463 |
| A | MN1620 |
| A | CL1621 |
| A | HOH2171 |
| A | HOH2174 |
| A | ALA197 |
| A | GLY198 |
| A | LYS199 |
| A | THR200 |
| A | LYS201 |
| A | ASN329 |
| A | ASN416 |
| A | ARG418 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP B1619 |
| Chain | Residue |
| B | GLY196 |
| B | ALA197 |
| B | GLY198 |
| B | LYS199 |
| B | THR200 |
| B | LYS201 |
| B | ASN329 |
| B | ASN416 |
| B | ARG418 |
| B | ARG463 |
| B | MN1620 |
| B | CL1621 |
| B | HOH2165 |
| B | HOH2166 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A1620 |
| Chain | Residue |
| A | THR200 |
| A | GLU285 |
| A | ADP1619 |
| A | HOH2171 |
| A | HOH2172 |
| A | HOH2173 |
| A | HOH2174 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B1620 |
| Chain | Residue |
| B | THR200 |
| B | GLU285 |
| B | ADP1619 |
| B | HOH2163 |
| B | HOH2164 |
| B | HOH2165 |
| B | HOH2166 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A1621 |
| Chain | Residue |
| A | ASN416 |
| A | ARG418 |
| A | ADP1619 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B1621 |
| Chain | Residue |
| B | ASN416 |
| B | PHE417 |
| B | ARG418 |
| B | ARG463 |
| B | ADP1619 |
| B | HOH2102 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A1622 |
| Chain | Residue |
| A | GLY168 |
| A | PRO174 |
| A | TYR176 |
| A | ILE442 |
| A | LEU443 |
| A | ALA598 |
| A | ALA602 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B1622 |
| Chain | Residue |
| B | GLY168 |
| B | PRO174 |
| B | ASP175 |
| B | TYR176 |
| B | ILE442 |
| B | LEU443 |
| B | ALA598 |
| B | ALA602 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 312 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 334 |
| Details | Domain: {"description":"Helicase C-terminal"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Region: {"description":"Important for RNA-binding","evidences":[{"source":"UniProtKB","id":"P14340","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Motif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Site: {"description":"Involved in NS3 ATPase and RTPase activities","evidences":[{"source":"UniProtKB","id":"P14335","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine; by host","evidences":[{"source":"UniProtKB","id":"Q32ZE1","evidenceCode":"ECO:0000250"}]} |
