2JL4
Holo structure of Maleyl Pyruvate Isomerase, a bacterial glutathione- s-transferase in Zeta class
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006559 | biological_process | L-phenylalanine catabolic process |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0009072 | biological_process | aromatic amino acid metabolic process |
| A | 0016034 | molecular_function | maleylacetoacetate isomerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0050077 | molecular_function | maleylpyruvate isomerase activity |
| A | 1901170 | biological_process | naphthalene catabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006559 | biological_process | L-phenylalanine catabolic process |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0009072 | biological_process | aromatic amino acid metabolic process |
| B | 0016034 | molecular_function | maleylacetoacetate isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0050077 | molecular_function | maleylpyruvate isomerase activity |
| B | 1901170 | biological_process | naphthalene catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE GSH A1213 |
| Chain | Residue |
| A | SER9 |
| A | PRO66 |
| A | HIS104 |
| A | ASN108 |
| A | ARG109 |
| A | ARG110 |
| A | HOH2230 |
| A | HOH2231 |
| A | HOH2232 |
| A | HOH2233 |
| A | HOH2234 |
| A | GLY10 |
| B | CYS101 |
| B | ASP102 |
| A | THR11 |
| A | ARG14 |
| A | HIS38 |
| A | LEU51 |
| A | VAL52 |
| A | GLN64 |
| A | SER65 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE GSH B1213 |
| Chain | Residue |
| A | ASP102 |
| A | HOH2118 |
| B | SER9 |
| B | GLY10 |
| B | THR11 |
| B | ARG14 |
| B | HIS38 |
| B | LEU51 |
| B | VAL52 |
| B | PRO53 |
| B | GLN64 |
| B | SER65 |
| B | PRO66 |
| B | HIS104 |
| B | ASN108 |
| B | ARG109 |
| B | ARG110 |
| B | HOH2095 |
| B | HOH2199 |
| B | HOH2200 |
| B | HOH2201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 158 |
| Details | Domain: {"description":"GST N-terminal","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 254 |
| Details | Domain: {"description":"GST C-terminal","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18824004","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| A | ASN5 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| B | ASN5 |
