2JKF
Plasmodium falciparum profilin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003779 | molecular_function | actin binding |
| A | 0003785 | molecular_function | actin monomer binding |
| A | 0005543 | molecular_function | phospholipid binding |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0008289 | molecular_function | lipid binding |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0030036 | biological_process | actin cytoskeleton organization |
| A | 0060327 | biological_process | cytoplasmic actin-based contraction involved in cell motility |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Region: {"description":"Pro-rich sequence-binding","evidences":[{"source":"UniProtKB","id":"P86294","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Region: {"description":"Actin-binding","evidences":[{"source":"UniProtKB","id":"P86294","evidenceCode":"ECO:0000250"},{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Motif: {"description":"Plasmodium-specific profilin mini-domain","evidences":[{"source":"UniProtKB","id":"P86294","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with Pro-rich sequence","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with actin","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
