2JIZ
The Structure of F1-ATPase inhibited by resveratrol.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005743 | cellular_component | mitochondrial inner membrane |
| A | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| A | 0005754 | cellular_component | mitochondrial proton-transporting ATP synthase, catalytic core |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006754 | biological_process | ATP biosynthetic process |
| A | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| A | 0032559 | molecular_function | adenyl ribonucleotide binding |
| A | 0043531 | molecular_function | ADP binding |
| A | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| A | 0046034 | biological_process | ATP metabolic process |
| A | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005743 | cellular_component | mitochondrial inner membrane |
| B | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| B | 0005754 | cellular_component | mitochondrial proton-transporting ATP synthase, catalytic core |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006754 | biological_process | ATP biosynthetic process |
| B | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| B | 0032559 | molecular_function | adenyl ribonucleotide binding |
| B | 0043531 | molecular_function | ADP binding |
| B | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| B | 0046034 | biological_process | ATP metabolic process |
| B | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| B | 1902600 | biological_process | proton transmembrane transport |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005743 | cellular_component | mitochondrial inner membrane |
| C | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| C | 0005754 | cellular_component | mitochondrial proton-transporting ATP synthase, catalytic core |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006754 | biological_process | ATP biosynthetic process |
| C | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| C | 0032559 | molecular_function | adenyl ribonucleotide binding |
| C | 0043531 | molecular_function | ADP binding |
| C | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| C | 0046034 | biological_process | ATP metabolic process |
| C | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| C | 1902600 | biological_process | proton transmembrane transport |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005743 | cellular_component | mitochondrial inner membrane |
| D | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| D | 0006754 | biological_process | ATP biosynthetic process |
| D | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0042776 | biological_process | proton motive force-driven mitochondrial ATP synthesis |
| D | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| D | 0046034 | biological_process | ATP metabolic process |
| D | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| D | 0046961 | molecular_function | proton-transporting ATPase activity, rotational mechanism |
| D | 1902600 | biological_process | proton transmembrane transport |
| E | 0005515 | molecular_function | protein binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005739 | cellular_component | mitochondrion |
| E | 0005743 | cellular_component | mitochondrial inner membrane |
| E | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| E | 0006754 | biological_process | ATP biosynthetic process |
| E | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| E | 0016887 | molecular_function | ATP hydrolysis activity |
| E | 0042776 | biological_process | proton motive force-driven mitochondrial ATP synthesis |
| E | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| E | 0046034 | biological_process | ATP metabolic process |
| E | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| E | 0046961 | molecular_function | proton-transporting ATPase activity, rotational mechanism |
| E | 1902600 | biological_process | proton transmembrane transport |
| F | 0005515 | molecular_function | protein binding |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005739 | cellular_component | mitochondrion |
| F | 0005743 | cellular_component | mitochondrial inner membrane |
| F | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| F | 0006754 | biological_process | ATP biosynthetic process |
| F | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| F | 0016887 | molecular_function | ATP hydrolysis activity |
| F | 0042776 | biological_process | proton motive force-driven mitochondrial ATP synthesis |
| F | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| F | 0046034 | biological_process | ATP metabolic process |
| F | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| F | 0046961 | molecular_function | proton-transporting ATPase activity, rotational mechanism |
| F | 1902600 | biological_process | proton transmembrane transport |
| G | 0000275 | cellular_component | mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) |
| G | 0005515 | molecular_function | protein binding |
| G | 0005739 | cellular_component | mitochondrion |
| G | 0005743 | cellular_component | mitochondrial inner membrane |
| G | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| G | 0006754 | biological_process | ATP biosynthetic process |
| G | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| G | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| G | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| G | 1902600 | biological_process | proton transmembrane transport |
| H | 0005515 | molecular_function | protein binding |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005739 | cellular_component | mitochondrion |
| H | 0005743 | cellular_component | mitochondrial inner membrane |
| H | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| H | 0005754 | cellular_component | mitochondrial proton-transporting ATP synthase, catalytic core |
| H | 0005886 | cellular_component | plasma membrane |
| H | 0006754 | biological_process | ATP biosynthetic process |
| H | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| H | 0032559 | molecular_function | adenyl ribonucleotide binding |
| H | 0043531 | molecular_function | ADP binding |
| H | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| H | 0046034 | biological_process | ATP metabolic process |
| H | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| H | 1902600 | biological_process | proton transmembrane transport |
| I | 0005515 | molecular_function | protein binding |
| I | 0005524 | molecular_function | ATP binding |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0005739 | cellular_component | mitochondrion |
| I | 0005743 | cellular_component | mitochondrial inner membrane |
| I | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| I | 0005754 | cellular_component | mitochondrial proton-transporting ATP synthase, catalytic core |
| I | 0005886 | cellular_component | plasma membrane |
| I | 0006754 | biological_process | ATP biosynthetic process |
| I | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| I | 0032559 | molecular_function | adenyl ribonucleotide binding |
| I | 0043531 | molecular_function | ADP binding |
| I | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| I | 0046034 | biological_process | ATP metabolic process |
| I | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| I | 1902600 | biological_process | proton transmembrane transport |
| J | 0005515 | molecular_function | protein binding |
| J | 0005524 | molecular_function | ATP binding |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0005739 | cellular_component | mitochondrion |
| J | 0005743 | cellular_component | mitochondrial inner membrane |
| J | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| J | 0005754 | cellular_component | mitochondrial proton-transporting ATP synthase, catalytic core |
| J | 0005886 | cellular_component | plasma membrane |
| J | 0006754 | biological_process | ATP biosynthetic process |
| J | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| J | 0032559 | molecular_function | adenyl ribonucleotide binding |
| J | 0043531 | molecular_function | ADP binding |
| J | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| J | 0046034 | biological_process | ATP metabolic process |
| J | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| J | 1902600 | biological_process | proton transmembrane transport |
| K | 0005515 | molecular_function | protein binding |
| K | 0005524 | molecular_function | ATP binding |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0005739 | cellular_component | mitochondrion |
| K | 0005743 | cellular_component | mitochondrial inner membrane |
| K | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| K | 0006754 | biological_process | ATP biosynthetic process |
| K | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| K | 0016887 | molecular_function | ATP hydrolysis activity |
| K | 0042776 | biological_process | proton motive force-driven mitochondrial ATP synthesis |
| K | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| K | 0046034 | biological_process | ATP metabolic process |
| K | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| K | 0046961 | molecular_function | proton-transporting ATPase activity, rotational mechanism |
| K | 1902600 | biological_process | proton transmembrane transport |
| L | 0005515 | molecular_function | protein binding |
| L | 0005524 | molecular_function | ATP binding |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0005739 | cellular_component | mitochondrion |
| L | 0005743 | cellular_component | mitochondrial inner membrane |
| L | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| L | 0006754 | biological_process | ATP biosynthetic process |
| L | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| L | 0016887 | molecular_function | ATP hydrolysis activity |
| L | 0042776 | biological_process | proton motive force-driven mitochondrial ATP synthesis |
| L | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| L | 0046034 | biological_process | ATP metabolic process |
| L | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| L | 0046961 | molecular_function | proton-transporting ATPase activity, rotational mechanism |
| L | 1902600 | biological_process | proton transmembrane transport |
| M | 0005515 | molecular_function | protein binding |
| M | 0005524 | molecular_function | ATP binding |
| M | 0005737 | cellular_component | cytoplasm |
| M | 0005739 | cellular_component | mitochondrion |
| M | 0005743 | cellular_component | mitochondrial inner membrane |
| M | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| M | 0006754 | biological_process | ATP biosynthetic process |
| M | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| M | 0016887 | molecular_function | ATP hydrolysis activity |
| M | 0042776 | biological_process | proton motive force-driven mitochondrial ATP synthesis |
| M | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| M | 0046034 | biological_process | ATP metabolic process |
| M | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| M | 0046961 | molecular_function | proton-transporting ATPase activity, rotational mechanism |
| M | 1902600 | biological_process | proton transmembrane transport |
| N | 0000275 | cellular_component | mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) |
| N | 0005515 | molecular_function | protein binding |
| N | 0005739 | cellular_component | mitochondrion |
| N | 0005743 | cellular_component | mitochondrial inner membrane |
| N | 0005753 | cellular_component | mitochondrial proton-transporting ATP synthase complex |
| N | 0006754 | biological_process | ATP biosynthetic process |
| N | 0015986 | biological_process | proton motive force-driven ATP synthesis |
| N | 0045261 | cellular_component | proton-transporting ATP synthase complex, catalytic core F(1) |
| N | 0046933 | molecular_function | proton-transporting ATP synthase activity, rotational mechanism |
| N | 1902600 | biological_process | proton transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE ANP A 1511 |
| Chain | Residue |
| A | ARG171 |
| A | GLN430 |
| A | GLN432 |
| A | MG1512 |
| A | HOH2142 |
| A | HOH2233 |
| A | HOH2331 |
| A | HOH2332 |
| A | HOH2333 |
| A | HOH2334 |
| A | HOH2335 |
| A | GLN172 |
| A | HOH2336 |
| A | HOH2337 |
| A | HOH2339 |
| D | TYR368 |
| D | HOH2238 |
| D | HOH2247 |
| D | HOH2250 |
| A | THR173 |
| A | GLY174 |
| A | LYS175 |
| A | THR176 |
| A | SER177 |
| A | PHE357 |
| A | PRO363 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1512 |
| Chain | Residue |
| A | THR176 |
| A | ANP1511 |
| A | HOH2142 |
| A | HOH2331 |
| A | HOH2339 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1513 |
| Chain | Residue |
| A | TYR244 |
| A | LEU245 |
| A | TYR248 |
| A | ARG304 |
| A | HOH2179 |
| A | HOH2340 |
| A | HOH2341 |
| A | HOH2342 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1514 |
| Chain | Residue |
| A | GLY290 |
| A | ARG291 |
| A | TYR294 |
| A | PRO295 |
| A | GLY296 |
| A | TYR337 |
| E | SER266 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ANP B 1510 |
| Chain | Residue |
| B | ARG171 |
| B | GLN172 |
| B | THR173 |
| B | GLY174 |
| B | LYS175 |
| B | THR176 |
| B | SER177 |
| B | PHE357 |
| B | ARG362 |
| B | GLN430 |
| B | GLN432 |
| B | MG1511 |
| B | HOH2157 |
| B | HOH2274 |
| B | HOH2275 |
| B | HOH2276 |
| B | HOH2277 |
| B | HOH2278 |
| B | HOH2279 |
| B | HOH2280 |
| E | ARG356 |
| E | ASP359 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 1511 |
| Chain | Residue |
| B | THR176 |
| B | ANP1510 |
| B | HOH2134 |
| B | HOH2157 |
| B | HOH2280 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 1512 |
| Chain | Residue |
| B | GLY130 |
| B | TYR244 |
| B | TYR248 |
| B | ARG304 |
| B | HOH2281 |
| B | HOH2282 |
| B | HOH2283 |
| B | HOH2284 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 1513 |
| Chain | Residue |
| B | GLY290 |
| B | ARG291 |
| B | TYR294 |
| B | GLY296 |
| B | TYR337 |
| F | SER266 |
| F | VAL279 |
| F | HOH2222 |
| site_id | AC9 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE ANP C 1511 |
| Chain | Residue |
| C | GLN432 |
| C | MG1512 |
| C | HOH2144 |
| C | HOH2342 |
| C | HOH2343 |
| C | HOH2344 |
| C | HOH2345 |
| C | HOH2346 |
| C | HOH2347 |
| C | HOH2348 |
| C | HOH2349 |
| C | HOH2350 |
| C | HOH2351 |
| F | HOH2258 |
| C | ARG171 |
| C | GLN172 |
| C | THR173 |
| C | GLY174 |
| C | LYS175 |
| C | THR176 |
| C | SER177 |
| C | PHE357 |
| C | ARG362 |
| C | GLN430 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 1512 |
| Chain | Residue |
| C | THR176 |
| C | ANP1511 |
| C | HOH2143 |
| C | HOH2144 |
| C | HOH2348 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL C 1513 |
| Chain | Residue |
| C | MET62 |
| C | GLY130 |
| C | TYR244 |
| C | TYR248 |
| C | ARG304 |
| C | HOH2221 |
| C | HOH2352 |
| C | HOH2353 |
| C | HOH2354 |
| site_id | BC3 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ADP D 1476 |
| Chain | Residue |
| C | SER372 |
| C | ARG373 |
| D | GLY159 |
| D | VAL160 |
| D | GLY161 |
| D | LYS162 |
| D | THR163 |
| D | VAL164 |
| D | TYR345 |
| D | PHE418 |
| D | ALA421 |
| D | PHE424 |
| D | THR425 |
| D | MG1477 |
| D | AZI1478 |
| D | HOH2126 |
| D | HOH2271 |
| D | HOH2295 |
| D | HOH2296 |
| D | HOH2297 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 1477 |
| Chain | Residue |
| D | THR163 |
| D | ADP1476 |
| D | HOH2134 |
| D | HOH2167 |
| D | HOH2295 |
| D | HOH2297 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AZI D 1478 |
| Chain | Residue |
| C | SER344 |
| C | ARG373 |
| D | ALA158 |
| D | GLY159 |
| D | LYS162 |
| D | ARG189 |
| D | TYR311 |
| D | ADP1476 |
| D | HOH2135 |
| D | HOH2297 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 1479 |
| Chain | Residue |
| A | HOH2011 |
| D | ARG231 |
| D | GLY265 |
| D | ARG274 |
| D | ASP288 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 E 1475 |
| Chain | Residue |
| E | GLY157 |
| E | ALA158 |
| E | GLY159 |
| E | VAL160 |
| E | GLY161 |
| E | LYS162 |
| E | THR163 |
| E | HOH2212 |
| site_id | BC8 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE ANP F 1475 |
| Chain | Residue |
| B | ILE343 |
| B | SER344 |
| B | VAL371 |
| B | ARG373 |
| F | ALA158 |
| F | GLY159 |
| F | VAL160 |
| F | GLY161 |
| F | LYS162 |
| F | THR163 |
| F | VAL164 |
| F | ARG189 |
| F | TYR345 |
| F | PHE418 |
| F | ALA421 |
| F | PHE424 |
| F | THR425 |
| F | MG1476 |
| F | HOH2131 |
| F | HOH2132 |
| F | HOH2177 |
| F | HOH2296 |
| F | HOH2324 |
| F | HOH2325 |
| F | HOH2326 |
| F | HOH2327 |
| F | HOH2328 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG F 1476 |
| Chain | Residue |
| F | THR163 |
| F | ANP1475 |
| F | HOH2132 |
| F | HOH2177 |
| F | HOH2328 |
| site_id | CC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE STL G 1273 |
| Chain | Residue |
| B | ARG291 |
| B | GLU292 |
| C | GLU292 |
| C | ALA293 |
| F | ALA278 |
| F | VAL279 |
| F | HOH2190 |
| G | ALA256 |
| G | THR259 |
| G | LYS260 |
| G | ILE263 |
| G | GLU264 |
| G | HOH2071 |
| G | HOH2072 |
| G | HOH2073 |
| G | HOH2074 |
| site_id | CC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE ANP H 1511 |
| Chain | Residue |
| H | ARG171 |
| H | GLN172 |
| H | THR173 |
| H | GLY174 |
| H | LYS175 |
| H | THR176 |
| H | SER177 |
| H | PHE357 |
| H | GLN430 |
| H | GLN432 |
| H | MG1512 |
| H | HOH2180 |
| H | HOH2323 |
| H | HOH2324 |
| H | HOH2325 |
| H | HOH2326 |
| H | HOH2327 |
| H | HOH2328 |
| H | HOH2329 |
| H | HOH2330 |
| H | HOH2331 |
| H | HOH2332 |
| K | HOH2271 |
| K | HOH2276 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG H 1512 |
| Chain | Residue |
| H | THR176 |
| H | ANP1511 |
| H | HOH2180 |
| H | HOH2322 |
| H | HOH2323 |
| site_id | CC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL H 1513 |
| Chain | Residue |
| H | TYR244 |
| H | LEU245 |
| H | TYR248 |
| H | ARG304 |
| H | HOH2020 |
| H | HOH2333 |
| H | HOH2334 |
| H | HOH2335 |
| H | HOH2336 |
| site_id | CC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL H 1514 |
| Chain | Residue |
| H | GLY290 |
| H | ARG291 |
| H | TYR294 |
| H | PRO295 |
| H | GLY296 |
| H | TYR337 |
| L | SER266 |
| site_id | CC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ANP I 1510 |
| Chain | Residue |
| I | ARG171 |
| I | GLN172 |
| I | THR173 |
| I | GLY174 |
| I | LYS175 |
| I | THR176 |
| I | SER177 |
| I | PHE357 |
| I | ARG362 |
| I | GLN430 |
| I | GLN432 |
| I | MG1511 |
| I | HOH2122 |
| I | HOH2172 |
| I | HOH2293 |
| I | HOH2294 |
| I | HOH2295 |
| I | HOH2296 |
| I | HOH2297 |
| L | ARG356 |
| L | ASP359 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG I 1511 |
| Chain | Residue |
| I | THR176 |
| I | ANP1510 |
| I | HOH2122 |
| I | HOH2172 |
| I | HOH2293 |
| site_id | CC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL I 1512 |
| Chain | Residue |
| I | GLY130 |
| I | TYR244 |
| I | TYR248 |
| I | ARG304 |
| I | HOH2023 |
| I | HOH2209 |
| I | HOH2298 |
| I | HOH2299 |
| site_id | CC9 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ANP J 1511 |
| Chain | Residue |
| J | ARG171 |
| J | GLN172 |
| J | THR173 |
| J | GLY174 |
| J | LYS175 |
| J | THR176 |
| J | SER177 |
| J | PHE357 |
| J | GLN430 |
| J | GLN432 |
| J | MG1512 |
| J | HOH2191 |
| J | HOH2242 |
| J | HOH2354 |
| J | HOH2355 |
| J | HOH2356 |
| J | HOH2357 |
| J | HOH2358 |
| J | HOH2359 |
| J | HOH2360 |
| J | HOH2361 |
| M | TYR368 |
| M | HOH2261 |
| site_id | DC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG J 1512 |
| Chain | Residue |
| J | THR176 |
| J | ANP1511 |
| J | HOH2146 |
| J | HOH2191 |
| J | HOH2354 |
| site_id | DC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL J 1513 |
| Chain | Residue |
| J | MET62 |
| J | GLY130 |
| J | TYR244 |
| J | TYR248 |
| J | ARG304 |
| J | HOH2181 |
| J | HOH2230 |
| J | HOH2362 |
| J | HOH2363 |
| site_id | DC3 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ADP K 1476 |
| Chain | Residue |
| J | SER372 |
| J | ARG373 |
| K | GLY159 |
| K | VAL160 |
| K | GLY161 |
| K | LYS162 |
| K | THR163 |
| K | VAL164 |
| K | TYR345 |
| K | PHE418 |
| K | ALA421 |
| K | PHE424 |
| K | THR425 |
| K | MG1477 |
| K | AZI1478 |
| K | HOH2132 |
| K | HOH2148 |
| K | HOH2328 |
| K | HOH2329 |
| K | HOH2330 |
| site_id | DC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG K 1477 |
| Chain | Residue |
| K | THR163 |
| K | ADP1476 |
| K | HOH2133 |
| K | HOH2144 |
| K | HOH2148 |
| K | HOH2328 |
| site_id | DC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AZI K 1478 |
| Chain | Residue |
| J | SER344 |
| J | ARG373 |
| K | ALA158 |
| K | GLY159 |
| K | LYS162 |
| K | ARG189 |
| K | TYR311 |
| K | ADP1476 |
| K | HOH2328 |
| K | HOH2332 |
| site_id | DC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL K 1479 |
| Chain | Residue |
| K | ARG231 |
| K | GLY265 |
| K | ARG274 |
| K | ASP288 |
| site_id | DC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL K 1480 |
| Chain | Residue |
| H | SER211 |
| H | GLN215 |
| K | SER127 |
| K | GLN130 |
| K | ASP330 |
| K | HOH2108 |
| K | HOH2111 |
| K | HOH2246 |
| site_id | DC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 L 1475 |
| Chain | Residue |
| L | ALA158 |
| L | GLY159 |
| L | GLY161 |
| L | LYS162 |
| L | THR163 |
| L | HOH2095 |
| L | HOH2248 |
| site_id | DC9 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE ANP M 1475 |
| Chain | Residue |
| I | ILE343 |
| I | SER344 |
| I | VAL371 |
| I | ARG373 |
| I | HOH2239 |
| M | ALA158 |
| M | GLY159 |
| M | VAL160 |
| M | GLY161 |
| M | LYS162 |
| M | THR163 |
| M | VAL164 |
| M | GLU188 |
| M | ARG189 |
| M | TYR345 |
| M | PHE418 |
| M | ALA421 |
| M | PHE424 |
| M | THR425 |
| M | MG1476 |
| M | HOH2131 |
| M | HOH2138 |
| M | HOH2174 |
| M | HOH2298 |
| M | HOH2330 |
| M | HOH2331 |
| M | HOH2332 |
| M | HOH2333 |
| site_id | EC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG M 1476 |
| Chain | Residue |
| M | THR163 |
| M | ANP1475 |
| M | HOH2138 |
| M | HOH2174 |
| M | HOH2330 |
| site_id | EC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE STL N 1273 |
| Chain | Residue |
| I | ARG291 |
| I | GLU292 |
| J | GLU292 |
| J | ALA293 |
| M | ALA278 |
| M | VAL279 |
| M | HOH2187 |
| N | THR259 |
| N | LYS260 |
| N | ILE263 |
| N | GLU264 |
| N | HOH2071 |
| N | HOH2072 |
| N | HOH2073 |
Functional Information from PROSITE/UniProt
| site_id | PS00153 |
| Number of Residues | 14 |
| Details | ATPASE_GAMMA ATP synthase gamma subunit signature. ITkEliEiisGAaA |
| Chain | Residue | Details |
| G | ILE258-ALA271 |
| site_id | PS00152 |
| Number of Residues | 10 |
| Details | ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PAINVGLSVS |
| Chain | Residue | Details |
| A | PRO363-SER372 | |
| D | PRO346-SER355 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q91VR2 |
| Chain | Residue | Details |
| G | LYS14 | |
| I | GLN430 | |
| J | ASP170 | |
| J | GLN430 | |
| N | LYS14 | |
| F | GLY157 | |
| K | GLY157 | |
| L | GLY157 | |
| M | GLY157 | |
| H | ASP170 | |
| H | GLN430 | |
| I | ASP170 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q91VR2 |
| Chain | Residue | Details |
| G | LYS24 | |
| G | LYS245 | |
| N | LYS24 | |
| N | LYS245 | |
| L | ARG189 | |
| M | ARG189 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P36542 |
| Chain | Residue | Details |
| G | LYS30 | |
| E | LYS472 | |
| F | LYS74 | |
| F | LYS111 | |
| F | LYS209 | |
| F | LYS214 | |
| F | LYS472 | |
| K | LYS74 | |
| K | LYS111 | |
| K | LYS209 | |
| K | LYS214 | |
| G | LYS172 | |
| K | LYS472 | |
| L | LYS74 | |
| L | LYS111 | |
| L | LYS209 | |
| L | LYS214 | |
| L | LYS472 | |
| M | LYS74 | |
| M | LYS111 | |
| M | LYS209 | |
| M | LYS214 | |
| N | LYS30 | |
| M | LYS472 | |
| N | LYS172 | |
| D | LYS472 | |
| E | LYS74 | |
| E | LYS111 | |
| E | LYS209 | |
| E | LYS214 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q91VR2 |
| Chain | Residue | Details |
| G | LYS90 | |
| L | LYS376 | |
| M | LYS148 | |
| M | LYS376 | |
| H | SER10 | |
| H | SER22 | |
| H | SER123 | |
| H | SER141 | |
| I | SER10 | |
| I | SER22 | |
| I | SER123 | |
| G | LYS129 | |
| I | SER141 | |
| J | SER10 | |
| J | SER22 | |
| J | SER123 | |
| J | SER141 | |
| N | LYS90 | |
| N | LYS129 | |
| F | LYS148 | |
| F | LYS376 | |
| K | LYS148 | |
| K | LYS376 | |
| L | LYS148 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P36542 |
| Chain | Residue | Details |
| G | SER121 | |
| N | SER121 | |
| F | THR262 | |
| K | THR262 | |
| L | THR262 | |
| M | THR262 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P06576 |
| Chain | Residue | Details |
| D | SER365 | |
| E | SER365 | |
| F | SER365 | |
| K | SER365 | |
| L | SER365 | |
| M | SER365 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P10719 |
| Chain | Residue | Details |
| D | SER383 | |
| B | LYS498 | |
| C | LYS80 | |
| C | LYS83 | |
| C | LYS89 | |
| C | LYS197 | |
| C | LYS498 | |
| H | LYS80 | |
| H | LYS83 | |
| H | LYS89 | |
| H | LYS197 | |
| E | SER383 | |
| H | LYS498 | |
| I | LYS80 | |
| I | LYS83 | |
| I | LYS89 | |
| I | LYS197 | |
| I | LYS498 | |
| J | LYS80 | |
| J | LYS83 | |
| J | LYS89 | |
| J | LYS197 | |
| F | SER383 | |
| J | LYS498 | |
| K | SER383 | |
| L | SER383 | |
| M | SER383 | |
| B | LYS83 | |
| B | LYS89 | |
| B | LYS197 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 12 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P56480 |
| Chain | Residue | Details |
| D | LYS430 | |
| L | LYS435 | |
| M | LYS430 | |
| M | LYS435 | |
| D | LYS435 | |
| E | LYS430 | |
| E | LYS435 | |
| F | LYS430 | |
| F | LYS435 | |
| K | LYS430 | |
| K | LYS435 | |
| L | LYS430 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 6 |
| Details | CARBOHYD: O-linked (GlcNAc) serine => ECO:0000250 |
| Chain | Residue | Details |
| D | SER56 | |
| A | LYS488 | |
| A | LYS496 | |
| B | LYS118 | |
| B | LYS124 | |
| B | LYS187 | |
| B | LYS196 | |
| B | LYS218 | |
| B | LYS262 | |
| B | LYS384 | |
| B | LYS455 | |
| E | SER56 | |
| B | LYS463 | |
| B | LYS488 | |
| B | LYS496 | |
| C | LYS118 | |
| C | LYS124 | |
| C | LYS187 | |
| C | LYS196 | |
| C | LYS218 | |
| C | LYS262 | |
| C | LYS384 | |
| F | SER56 | |
| C | LYS455 | |
| C | LYS463 | |
| C | LYS488 | |
| C | LYS496 | |
| H | LYS118 | |
| H | LYS124 | |
| H | LYS187 | |
| H | LYS196 | |
| H | LYS218 | |
| H | LYS262 | |
| K | SER56 | |
| H | LYS384 | |
| H | LYS455 | |
| H | LYS463 | |
| H | LYS488 | |
| H | LYS496 | |
| I | LYS118 | |
| I | LYS124 | |
| I | LYS187 | |
| I | LYS196 | |
| I | LYS218 | |
| L | SER56 | |
| I | LYS262 | |
| I | LYS384 | |
| I | LYS455 | |
| I | LYS463 | |
| I | LYS488 | |
| I | LYS496 | |
| J | LYS118 | |
| J | LYS124 | |
| J | LYS187 | |
| J | LYS196 | |
| M | SER56 | |
| J | LYS218 | |
| J | LYS262 | |
| J | LYS384 | |
| J | LYS455 | |
| J | LYS463 | |
| J | LYS488 | |
| J | LYS496 | |
| A | LYS384 | |
| A | LYS455 | |
| A | LYS463 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 6 |
| Details | MOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:Q03265 |
| Chain | Residue | Details |
| A | ARG161 | |
| B | ARG161 | |
| C | ARG161 | |
| H | ARG161 | |
| I | ARG161 | |
| J | ARG161 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 6 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P25705 |
| Chain | Residue | Details |
| A | LYS391 | |
| B | LYS391 | |
| C | LYS391 | |
| H | LYS391 | |
| I | LYS391 | |
| J | LYS391 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 6 |
| Details | CARBOHYD: O-linked (GlcNAc) serine; alternate => ECO:0000250 |
| Chain | Residue | Details |
| A | SER33 | |
| B | SER33 | |
| C | SER33 | |
| H | SER33 | |
| I | SER33 | |
| J | SER33 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| D | ARG356 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| E | ARG356 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| F | ARG356 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| K | ARG356 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| L | ARG356 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| M | ARG356 |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| C | ARG373 | |
| D | ARG189 | |
| D | GLU188 | |
| D | LYS162 |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| A | ARG373 | |
| E | ARG189 | |
| E | GLU188 | |
| E | LYS162 |
| site_id | CSA9 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| F | ARG189 | |
| F | GLU188 | |
| F | LYS162 | |
| B | ARG373 |
| site_id | CSA10 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| J | ARG373 | |
| K | ARG189 | |
| K | GLU188 | |
| K | LYS162 |
| site_id | CSA11 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| H | ARG373 | |
| L | ARG189 | |
| L | GLU188 | |
| L | LYS162 |
| site_id | CSA12 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| M | ARG189 | |
| M | GLU188 | |
| M | LYS162 | |
| I | ARG373 |
| site_id | CSA13 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| A | LYS175 | |
| A | LYS209 | |
| A | GLN208 |
| site_id | CSA14 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| B | LYS175 | |
| B | LYS209 | |
| B | GLN208 |
| site_id | CSA15 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| C | LYS175 | |
| C | LYS209 | |
| C | GLN208 |
| site_id | CSA16 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| H | LYS175 | |
| H | LYS209 | |
| H | GLN208 |
| site_id | CSA17 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| I | LYS175 | |
| I | LYS209 | |
| I | GLN208 |
| site_id | CSA18 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ohh |
| Chain | Residue | Details |
| J | LYS175 | |
| J | LYS209 | |
| J | GLN208 |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 178 |
| Chain | Residue | Details |
| D | LYS162 | electrostatic stabiliser |
| D | GLU188 | electrostatic stabiliser |
| D | ARG189 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 178 |
| Chain | Residue | Details |
| E | LYS162 | electrostatic stabiliser |
| E | GLU188 | electrostatic stabiliser |
| E | ARG189 | electrostatic stabiliser |
| site_id | MCSA3 |
| Number of Residues | 3 |
| Details | M-CSA 178 |
| Chain | Residue | Details |
| F | LYS162 | electrostatic stabiliser |
| F | GLU188 | electrostatic stabiliser |
| F | ARG189 | electrostatic stabiliser |
| site_id | MCSA4 |
| Number of Residues | 3 |
| Details | M-CSA 178 |
| Chain | Residue | Details |
| K | LYS162 | electrostatic stabiliser |
| K | GLU188 | electrostatic stabiliser |
| K | ARG189 | electrostatic stabiliser |
| site_id | MCSA5 |
| Number of Residues | 3 |
| Details | M-CSA 178 |
| Chain | Residue | Details |
| L | LYS162 | electrostatic stabiliser |
| L | GLU188 | electrostatic stabiliser |
| L | ARG189 | electrostatic stabiliser |
| site_id | MCSA6 |
| Number of Residues | 3 |
| Details | M-CSA 178 |
| Chain | Residue | Details |
| M | LYS162 | electrostatic stabiliser |
| M | GLU188 | electrostatic stabiliser |
| M | ARG189 | electrostatic stabiliser |
