2JFT

Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with sulfate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004722	molecular_function	protein serine/threonine phosphatase activity
A	0005829	cellular_component	cytosol
A	0006470	biological_process	protein dephosphorylation
A	0032873	biological_process	negative regulation of stress-activated MAPK cascade
A	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
A	0043124	biological_process	negative regulation of canonical NF-kappaB signal transduction
A	0046872	molecular_function	metal ion binding
A	0090263	biological_process	positive regulation of canonical Wnt signaling pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A1234

Chain	Residue
A	ASP35
A	GLY36
A	HOH544
A	HOH496
A	HOH451
A	HOH470

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN A1235

Chain	Residue
A	MG303
A	HOH451
A	HOH579
A	HOH568
A	ASP35
A	ASP185
A	ASP223

---

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MG A1236

Chain	Residue
A	ASP111
A	ASP185
A	MN302
A	MG304
A	HOH531
A	HOH464
A	HOH520
A	HOH512
A	HOH579

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A1237

Chain	Residue
A	ASP111
A	ASP185
A	MG303
A	MG305
A	HOH428
A	HOH464
A	HOH455
A	HOH523

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG A1238

Chain	Residue
A	ASP185
A	MG304
A	HOH455
A	HOH686
A	HOH551
A	HOH512
A	HOH559

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 A1239

Chain	Residue
A	ARG17
A	PHE37
A	HOH640
A	HOH520
A	HOH451
A	HOH579
A	HOH470
A	HOH457
A	HOH452
A	HOH484

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 506

Chain	Residue
A	HOH696
A	HOH494
A	HOH680
A	HOH736
A	HOH700
A	HOH669

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