2JFE

The crystal structure of human cytosolic beta-glucosidase

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0004336	molecular_function	galactosylceramidase activity
X	0004348	molecular_function	glucosylceramidase activity
X	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
X	0004565	molecular_function	beta-galactosidase activity
X	0005515	molecular_function	protein binding
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005975	biological_process	carbohydrate metabolic process
X	0006629	biological_process	lipid metabolic process
X	0006680	biological_process	glucosylceramide catabolic process
X	0006683	biological_process	galactosylceramide catabolic process
X	0008422	molecular_function	beta-glucosidase activity
X	0009313	biological_process	oligosaccharide catabolic process
X	0016020	cellular_component	membrane
X	0016139	biological_process	glycoside catabolic process
X	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
X	0017042	molecular_function	glycosylceramidase activity
X	0046477	biological_process	glycosylceramide catabolic process
X	0046479	biological_process	glycosphingolipid catabolic process
X	0050821	biological_process	protein stabilization
X	1901805	biological_process	beta-glucoside catabolic process
X	1902494	cellular_component	catalytic complex
X	1903017	biological_process	positive regulation of exo-alpha-sialidase activity

Functional Information from PROSITE/UniProt

site_id	PS00653
Number of Residues	15
Details	GLYCOSYL_HYDROL_F1_2 Glycosyl hydrolases family 1 N-terminal signature. FgWAaAtAAYQvEgG

Chain	Residue	Details
X	PHE7-GLY21

Functional Information from SwissProt/UniProt

Chain	Residue	Details
X	GLU165

Chain	Residue	Details
X	GLU373

Chain	Residue	Details
X	GLU424

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1cbg

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1cbg