2JEB

Structure of a 9-subunit archaeal exosome bound to Mn ions

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000177	cellular_component	cytoplasmic exosome (RNase complex)
A	0000178	cellular_component	exosome (RNase complex)
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006401	biological_process	RNA catabolic process
A	0016075	biological_process	rRNA catabolic process
A	0035925	molecular_function	mRNA 3'-UTR AU-rich region binding
B	0000175	molecular_function	3'-5'-RNA exonuclease activity
B	0000177	cellular_component	cytoplasmic exosome (RNase complex)
B	0000178	cellular_component	exosome (RNase complex)
B	0000956	biological_process	nuclear-transcribed mRNA catabolic process
B	0003723	molecular_function	RNA binding
B	0004518	molecular_function	nuclease activity
B	0004527	molecular_function	exonuclease activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006401	biological_process	RNA catabolic process
B	0010467	biological_process	gene expression
B	0016075	biological_process	rRNA catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
B	1902494	cellular_component	catalytic complex
I	0000178	cellular_component	exosome (RNase complex)
I	0000467	biological_process	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
I	0003676	molecular_function	nucleic acid binding
I	0003723	molecular_function	RNA binding
I	0005737	cellular_component	cytoplasm
I	0006401	biological_process	RNA catabolic process
I	0008143	molecular_function	poly(A) binding
I	0034475	biological_process	U4 snRNA 3'-end processing
I	0071034	biological_process	CUT catabolic process
I	0071051	biological_process	poly(A)-dependent snoRNA 3'-end processing

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MN A 301

Chain	Residue
A	ASP72

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 301

Chain	Residue
B	GLY137
B	SER138
B	ARG139

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MN I 301

Chain	Residue
B	HOH2037

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 1PE A 401

Chain	Residue
A	THR43
A	LEU55
A	LYS57

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