2JCO

Crystal structure of wild type alpha-1,3 Galactosyltransferase in the absence of ligands

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005975	biological_process	carbohydrate metabolic process
A	0016020	cellular_component	membrane
A	0016758	molecular_function	hexosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A1359

Chain	Residue
A	LYS126
A	THR128
A	HIS216
A	GLU217
A	ASP219

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"11179209","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1G8O","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11179209","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11592969","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12011052","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1G93","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GX4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K4V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O7O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O7Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VZX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JCK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VS4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WGZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11179209","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11592969","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12011052","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1G8O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1G93","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GX0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GX4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K4V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O7O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O7Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VZT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VZU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VZX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JCK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VS4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VS5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WGZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12011052","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GX4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O7O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O7Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VZX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VS4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WGZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1g8o

Chain	Residue	Details
A	GLU317

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1g8o

Chain	Residue	Details
A	GLU317
A	TRP314

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site_id	MCSA1
Number of Residues	5
Details	M-CSA 356

Chain	Residue	Details
A	GLN247	electrostatic stabiliser, hydrogen bond donor
A	HIS280	electrostatic stabiliser, hydrogen bond donor
A	TRP314	electrostatic stabiliser, hydrogen bond donor
A	GLU317	activator, covalently attached, electrostatic stabiliser, nucleofuge, nucleophile
A	TRP356	electrostatic stabiliser, hydrogen bond donor

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