2JCB
The crystal structure of 5-formyl-tetrahydrofolate cycloligase from Bacillus anthracis (BA4489)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008150 | biological_process | biological_process |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0030272 | molecular_function | 5-formyltetrahydrofolate cyclo-ligase activity |
| A | 0035999 | biological_process | tetrahydrofolate interconversion |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008150 | biological_process | biological_process |
| B | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| B | 0030272 | molecular_function | 5-formyltetrahydrofolate cyclo-ligase activity |
| B | 0035999 | biological_process | tetrahydrofolate interconversion |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1191 |
| Chain | Residue |
| A | ARG135 |
| A | HOH2201 |
| A | HOH2202 |
| A | GLY137 |
| A | TYR138 |
| A | GLY140 |
| A | GLY141 |
| A | TYR142 |
| A | TYR143 |
| A | ADP1190 |
| A | HOH2200 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1192 |
| Chain | Residue |
| A | LYS5 |
| A | ASP144 |
| A | ASP173 |
| A | ADP1190 |
| A | HOH2157 |
| A | HOH2198 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1190 |
| Chain | Residue |
| B | ARG135 |
| B | GLY137 |
| B | TYR138 |
| B | GLY141 |
| B | TYR142 |
| B | TYR143 |
| B | ADP1189 |
| B | HOH2121 |
| B | HOH2122 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 1191 |
| Chain | Residue |
| B | ASP144 |
| B | ASP173 |
| B | ADP1189 |
| B | HOH2092 |
| B | HOH2120 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ADP A 1190 |
| Chain | Residue |
| A | ARG2 |
| A | LYS5 |
| A | ARG9 |
| A | GLY137 |
| A | TYR138 |
| A | GLY139 |
| A | GLY140 |
| A | GLY141 |
| A | ASP144 |
| A | ARG145 |
| A | PHE172 |
| A | ASP173 |
| A | PO41191 |
| A | MG1192 |
| A | HOH2024 |
| A | HOH2178 |
| A | HOH2197 |
| A | HOH2198 |
| A | HOH2199 |
| A | HOH2200 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ADP B 1189 |
| Chain | Residue |
| B | ARG2 |
| B | LYS5 |
| B | ARG9 |
| B | ILE136 |
| B | GLY137 |
| B | TYR138 |
| B | GLY139 |
| B | GLY140 |
| B | GLY141 |
| B | ASP144 |
| B | ARG145 |
| B | PHE172 |
| B | ASP173 |
| B | PO41190 |
| B | MG1191 |
| B | HOH2093 |
| B | HOH2120 |
| B | HOH2121 |
