2JBW
Crystal Structure of the 2,6-dihydroxy-pseudo-oxynicotine Hydrolase.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009820 | biological_process | alkaloid metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019608 | biological_process | nicotine catabolic process |
| B | 0009820 | biological_process | alkaloid metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019608 | biological_process | nicotine catabolic process |
| C | 0009820 | biological_process | alkaloid metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0019608 | biological_process | nicotine catabolic process |
| D | 0009820 | biological_process | alkaloid metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0019608 | biological_process | nicotine catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A1368 |
| Chain | Residue |
| A | LEU200 |
| A | THR201 |
| A | LEU203 |
| A | ILE206 |
| A | ASN208 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B1367 |
| Chain | Residue |
| B | ASN208 |
| B | HOH2096 |
| B | LEU200 |
| B | THR201 |
| B | LEU203 |
| B | ILE206 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA C1367 |
| Chain | Residue |
| C | LEU200 |
| C | THR201 |
| C | LEU203 |
| C | ILE206 |
| C | ASN208 |
| C | HOH2167 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA D1367 |
| Chain | Residue |
| D | LEU200 |
| D | LEU203 |
| D | ILE206 |
| D | ASN208 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255, ECO:0000303|PubMed:17275835 |
| Chain | Residue | Details |
| A | GLU148 | |
| B | GLU148 | |
| C | GLU148 | |
| D | GLU148 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:17275835 |
| Chain | Residue | Details |
| A | SER217 | |
| D | SER217 | |
| D | ASP300 | |
| D | HIS329 | |
| A | ASP300 | |
| A | HIS329 | |
| B | SER217 | |
| B | ASP300 | |
| B | HIS329 | |
| C | SER217 | |
| C | ASP300 | |
| C | HIS329 |
