2JAI

DDAH1 complexed with citrulline

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000052	biological_process	citrulline metabolic process
A	0003073	biological_process	regulation of systemic arterial blood pressure
A	0003824	molecular_function	catalytic activity
A	0005829	cellular_component	cytosol
A	0006525	biological_process	arginine metabolic process
A	0006527	biological_process	L-arginine catabolic process
A	0007263	biological_process	nitric oxide mediated signal transduction
A	0008285	biological_process	negative regulation of cell population proliferation
A	0016403	molecular_function	dimethylargininase activity
A	0016597	molecular_function	amino acid binding
A	0016787	molecular_function	hydrolase activity
A	0043116	biological_process	negative regulation of vascular permeability
A	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
A	0045766	biological_process	positive regulation of angiogenesis
A	0046209	biological_process	nitric oxide metabolic process
A	0046872	molecular_function	metal ion binding
A	0070062	cellular_component	extracellular exosome
A	1900038	biological_process	negative regulation of cellular response to hypoxia
B	0000052	biological_process	citrulline metabolic process
B	0003073	biological_process	regulation of systemic arterial blood pressure
B	0003824	molecular_function	catalytic activity
B	0005829	cellular_component	cytosol
B	0006525	biological_process	arginine metabolic process
B	0006527	biological_process	L-arginine catabolic process
B	0007263	biological_process	nitric oxide mediated signal transduction
B	0008285	biological_process	negative regulation of cell population proliferation
B	0016403	molecular_function	dimethylargininase activity
B	0016597	molecular_function	amino acid binding
B	0016787	molecular_function	hydrolase activity
B	0043116	biological_process	negative regulation of vascular permeability
B	0045429	biological_process	positive regulation of nitric oxide biosynthetic process
B	0045766	biological_process	positive regulation of angiogenesis
B	0046209	biological_process	nitric oxide metabolic process
B	0046872	molecular_function	metal ion binding
B	0070062	cellular_component	extracellular exosome
B	1900038	biological_process	negative regulation of cellular response to hypoxia

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE CIR A1281

Chain	Residue
A	LEU29
A	ASP268
A	LEU270
A	CYS273
A	HOH2114
A	ASP72
A	GLU77
A	ASP78
A	ARG97
A	GLY128
A	ARG144
A	HIS172
A	VAL267

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"19663506","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	10
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"UniProtKB","id":"P56965","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"9874257","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1jdw

Chain	Residue	Details
A	CYS273
A	ASP126

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1jdw

Chain	Residue	Details
B	CYS273
B	ASP126

---