2JAC
Glutaredoxin Grx1p C30S mutant from yeast
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0004602 | molecular_function | glutathione peroxidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0015038 | molecular_function | glutathione disulfide oxidoreductase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE GSH A 1000 |
| Chain | Residue |
| A | LYS24 |
| A | GLY87 |
| A | ASN88 |
| A | ASP89 |
| A | HOH2014 |
| A | HOH3003 |
| A | HOH3004 |
| A | HOH3005 |
| A | HOH3006 |
| A | HOH3007 |
| A | HOH3007 |
| A | TYR26 |
| A | HOH3008 |
| A | CYS27 |
| A | PRO28 |
| A | TYR29 |
| A | GLN63 |
| A | THR74 |
| A | VAL75 |
| A | PRO76 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17327665, ECO:0000269|PubMed:18473363 |
| Chain | Residue | Details |
| A | LYS24 | |
| A | GLN63 | |
| A | VAL75 | |
| A | ASN88 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: S-glutathionyl cysteine; alternate => ECO:0000269|PubMed:17327665, ECO:0000269|PubMed:18473363 |
| Chain | Residue | Details |
| A | CYS27 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047 |
| Chain | Residue | Details |
| A | LYS11 |
