Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004797 | molecular_function | thymidine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006259 | biological_process | DNA metabolic process |
A | 0008270 | molecular_function | zinc ion binding |
A | 0009157 | biological_process | deoxyribonucleoside monophosphate biosynthetic process |
A | 0016301 | molecular_function | kinase activity |
A | 0016310 | biological_process | phosphorylation |
A | 0046104 | biological_process | thymidine metabolic process |
A | 0046872 | molecular_function | metal ion binding |
A | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A1192 |
Chain | Residue |
A | CYS145 |
A | CYS148 |
A | CYS183 |
A | CYS186 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE TTP A1193 |
Chain | Residue |
A | SER22 |
A | GLU23 |
A | PHE34 |
A | VAL56 |
A | SER57 |
A | HIS58 |
A | ASN59 |
A | ASP88 |
A | GLU89 |
A | VAL144 |
A | HOH2009 |
A | HOH2020 |
A | SER16 |
A | PHE18 |
A | SER19 |
A | GLY20 |
A | LYS21 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE MPD A1194 |
Chain | Residue |
A | PHE92 |
A | LEU116 |
A | ASP119 |
A | PHE120 |
A | PHE125 |
A | ILE170 |
A | TYR179 |
Functional Information from PROSITE/UniProt
site_id | PS00603 |
Number of Residues | 14 |
Details | TK_CELLULAR_TYPE Thymidine kinase cellular-type signature. GasEsYePrCRhCH |
Chain | Residue | Details |
A | GLY174-HIS187 | |