Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE BEN A 1241 |
| Chain | Residue |
| A | ASP186 |
| A | GLY219 |
| A | HOH2183 |
| A | SER187 |
| A | CYS188 |
| A | GLN189 |
| A | SER192 |
| A | VAL206 |
| A | TRP208 |
| A | GLY209 |
| A | GLY211 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IPH A 1242 |
| Chain | Residue |
| A | SER59 |
| A | SER145 |
| A | TYR146 |
| A | ASP148 |
| A | HOH2047 |
| A | HOH2193 |
| A | HOH2195 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1239 |
| Chain | Residue |
| A | GLU67 |
| A | ASN69 |
| A | VAL72 |
| A | GLU77 |
| A | HOH2051 |
| A | HOH2061 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 1240 |
| Chain | Residue |
| A | THR122 |
| A | SER123 |
| A | GLY143 |
| A | HOH2075 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL51-CYS56 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP186-VAL197 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | LYS58 | |
| A | LEU102 | |
| A | PRO195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ILE70 | |
| A | VAL72 | |
| A | GLY75 | |
| A | ILE80 | |
| A | GLN189 | |
| A | SER192 | |
| A | PRO195 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP99 | |
| A | HIS55 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER192 | |
| A | GLY193 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER192 | |
| A | GLY190 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER192 | |
| A | ASP99 | |
| A | HIS55 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER192 | |
| A | ASP99 | |
| A | HIS55 | |
| A | GLY190 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER192 | |
| A | GLY193 | |
| A | ASP99 | |
| A | HIS55 | |
