2J9D
Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006808 | biological_process | regulation of nitrogen utilization |
| A | 0030234 | molecular_function | enzyme regulator activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006808 | biological_process | regulation of nitrogen utilization |
| B | 0030234 | molecular_function | enzyme regulator activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006808 | biological_process | regulation of nitrogen utilization |
| C | 0030234 | molecular_function | enzyme regulator activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006808 | biological_process | regulation of nitrogen utilization |
| D | 0030234 | molecular_function | enzyme regulator activity |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0005515 | molecular_function | protein binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006808 | biological_process | regulation of nitrogen utilization |
| E | 0030234 | molecular_function | enzyme regulator activity |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0005515 | molecular_function | protein binding |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006808 | biological_process | regulation of nitrogen utilization |
| F | 0030234 | molecular_function | enzyme regulator activity |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0005515 | molecular_function | protein binding |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005829 | cellular_component | cytosol |
| G | 0006808 | biological_process | regulation of nitrogen utilization |
| G | 0030234 | molecular_function | enzyme regulator activity |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0005515 | molecular_function | protein binding |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005829 | cellular_component | cytosol |
| H | 0006808 | biological_process | regulation of nitrogen utilization |
| H | 0030234 | molecular_function | enzyme regulator activity |
| I | 0000166 | molecular_function | nucleotide binding |
| I | 0005515 | molecular_function | protein binding |
| I | 0005524 | molecular_function | ATP binding |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0005829 | cellular_component | cytosol |
| I | 0006808 | biological_process | regulation of nitrogen utilization |
| I | 0030234 | molecular_function | enzyme regulator activity |
| J | 0000166 | molecular_function | nucleotide binding |
| J | 0005515 | molecular_function | protein binding |
| J | 0005524 | molecular_function | ATP binding |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0005829 | cellular_component | cytosol |
| J | 0006808 | biological_process | regulation of nitrogen utilization |
| J | 0030234 | molecular_function | enzyme regulator activity |
| K | 0000166 | molecular_function | nucleotide binding |
| K | 0005515 | molecular_function | protein binding |
| K | 0005524 | molecular_function | ATP binding |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0005829 | cellular_component | cytosol |
| K | 0006808 | biological_process | regulation of nitrogen utilization |
| K | 0030234 | molecular_function | enzyme regulator activity |
| L | 0000166 | molecular_function | nucleotide binding |
| L | 0005515 | molecular_function | protein binding |
| L | 0005524 | molecular_function | ATP binding |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0005829 | cellular_component | cytosol |
| L | 0006808 | biological_process | regulation of nitrogen utilization |
| L | 0030234 | molecular_function | enzyme regulator activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A1116 |
| Chain | Residue |
| A | LYS3 |
| A | GLU5 |
| B | LYS3 |
| B | GLU5 |
| C | LYS3 |
| C | GLU5 |
| C | ILE94 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A1117 |
| Chain | Residue |
| A | GLY87 |
| A | ASP88 |
| A | HOH2043 |
| A | HOH2057 |
| C | ARG101 |
| C | ARG103 |
| A | ASN85 |
| A | PRO86 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT E1116 |
| Chain | Residue |
| D | LYS3 |
| D | GLU5 |
| D | ILE94 |
| E | LYS3 |
| E | GLU5 |
| F | LYS3 |
| F | GLU5 |
| F | ILE94 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT H1113 |
| Chain | Residue |
| G | LYS3 |
| G | GLU5 |
| G | ILE94 |
| H | LYS3 |
| H | GLU5 |
| I | LYS3 |
| I | GLU5 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL J1114 |
| Chain | Residue |
| J | LYS60 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT J1116 |
| Chain | Residue |
| J | LYS3 |
| J | GLU5 |
| K | LYS3 |
| K | GLU5 |
| L | LYS3 |
| L | GLU5 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ADP B1115 |
| Chain | Residue |
| B | GLY27 |
| B | MET28 |
| B | THR29 |
| B | GLU62 |
| B | LEU63 |
| B | VAL64 |
| B | ARG101 |
| B | ARG103 |
| B | HOH2077 |
| B | HOH2078 |
| C | ILE7 |
| C | GLY35 |
| C | ARG36 |
| C | GLY37 |
| C | VAL38 |
| C | LYS58 |
| C | GLY87 |
| C | ASP88 |
| C | GLY89 |
| C | LYS90 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE AMP E1115 |
| Chain | Residue |
| E | GLY27 |
| E | MET28 |
| E | THR29 |
| E | GLU62 |
| E | LEU63 |
| E | VAL64 |
| E | ARG101 |
| E | GLU114 |
| F | ILE7 |
| F | GLY35 |
| F | VAL38 |
| F | LYS58 |
| F | GLY87 |
| F | ASP88 |
| F | GLY89 |
| F | LYS90 |
| site_id | AC9 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ADP I1115 |
| Chain | Residue |
| H | GLY27 |
| H | THR29 |
| H | GLU62 |
| H | LEU63 |
| H | VAL64 |
| H | ARG101 |
| H | ARG103 |
| I | ILE7 |
| I | GLY35 |
| I | ARG36 |
| I | LYS58 |
| I | ASN85 |
| I | PRO86 |
| I | GLY87 |
| I | ASP88 |
| I | GLY89 |
| I | LYS90 |
| I | PHE92 |
| I | HOH2040 |
| I | HOH2041 |
| site_id | BC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ADP J1115 |
| Chain | Residue |
| J | PRO86 |
| J | GLY87 |
| J | ASP88 |
| J | GLY89 |
| J | LYS90 |
| J | HOH2043 |
| J | HOH2044 |
| L | GLY27 |
| L | THR29 |
| L | GLU62 |
| L | LEU63 |
| L | VAL64 |
| L | ARG101 |
| L | ARG103 |
| J | ILE7 |
| J | GLY35 |
| J | ARG36 |
| J | GLY37 |
| J | VAL38 |
| J | LYS58 |
| site_id | BC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ADP L1114 |
| Chain | Residue |
| K | GLY27 |
| K | MET28 |
| K | THR29 |
| K | GLU62 |
| K | LEU63 |
| K | VAL64 |
| K | ARG101 |
| K | ARG103 |
| K | GLU114 |
| L | ILE7 |
| L | GLY35 |
| L | ARG36 |
| L | GLY37 |
| L | VAL38 |
| L | GLN39 |
| L | LYS58 |
| L | GLY87 |
| L | ASP88 |
| L | GLY89 |
| L | LYS90 |
| L | HOH2072 |
| L | HOH2073 |
Functional Information from PROSITE/UniProt
| site_id | PS00638 |
| Number of Residues | 14 |
| Details | PII_GLNB_CTER P-II protein C-terminal region signature. TgnpGDGKIFVipV |
| Chain | Residue | Details |
| A | THR83-VAL96 | |
| E | THR83-VAL96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17203075, ECO:0007744|PDB:2J9C, ECO:0007744|PDB:2J9E |
| Chain | Residue | Details |
| E | THR29 | |
| B | ARG101 | |
| C | THR29 | |
| C | VAL38 | |
| C | VAL64 | |
| C | PRO86 | |
| C | ARG101 | |
| D | THR29 | |
| D | VAL38 | |
| D | VAL64 | |
| D | PRO86 | |
| E | VAL38 | |
| D | ARG101 | |
| F | THR29 | |
| F | VAL38 | |
| F | VAL64 | |
| F | PRO86 | |
| F | ARG101 | |
| G | THR29 | |
| G | VAL38 | |
| G | VAL64 | |
| G | PRO86 | |
| E | VAL64 | |
| G | ARG101 | |
| H | THR29 | |
| H | VAL38 | |
| H | VAL64 | |
| H | PRO86 | |
| H | ARG101 | |
| I | THR29 | |
| I | VAL38 | |
| I | VAL64 | |
| I | PRO86 | |
| E | PRO86 | |
| I | ARG101 | |
| J | THR29 | |
| J | VAL38 | |
| J | VAL64 | |
| J | PRO86 | |
| J | ARG101 | |
| K | THR29 | |
| K | VAL38 | |
| K | VAL64 | |
| K | PRO86 | |
| E | ARG101 | |
| K | ARG101 | |
| L | THR29 | |
| L | VAL38 | |
| L | VAL64 | |
| L | PRO86 | |
| L | ARG101 | |
| B | THR29 | |
| B | VAL38 | |
| B | VAL64 | |
| B | PRO86 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17203075 |
| Chain | Residue | Details |
| E | ILE52 | |
| K | ILE52 | |
| L | ILE52 | |
| B | ILE52 | |
| C | ILE52 | |
| D | ILE52 | |
| F | ILE52 | |
| G | ILE52 | |
| H | ILE52 | |
| I | ILE52 | |
| J | ILE52 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17203075, ECO:0007744|PDB:2J9D |
| Chain | Residue | Details |
| E | ASP88 | |
| K | ASP88 | |
| L | ASP88 | |
| B | ASP88 | |
| C | ASP88 | |
| D | ASP88 | |
| F | ASP88 | |
| G | ASP88 | |
| H | ASP88 | |
| I | ASP88 | |
| J | ASP88 |
