2J9D

Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006808	biological_process	regulation of nitrogen utilization
A	0030234	molecular_function	enzyme regulator activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006808	biological_process	regulation of nitrogen utilization
B	0030234	molecular_function	enzyme regulator activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006808	biological_process	regulation of nitrogen utilization
C	0030234	molecular_function	enzyme regulator activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006808	biological_process	regulation of nitrogen utilization
D	0030234	molecular_function	enzyme regulator activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006808	biological_process	regulation of nitrogen utilization
E	0030234	molecular_function	enzyme regulator activity
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006808	biological_process	regulation of nitrogen utilization
F	0030234	molecular_function	enzyme regulator activity
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006808	biological_process	regulation of nitrogen utilization
G	0030234	molecular_function	enzyme regulator activity
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006808	biological_process	regulation of nitrogen utilization
H	0030234	molecular_function	enzyme regulator activity
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006808	biological_process	regulation of nitrogen utilization
I	0030234	molecular_function	enzyme regulator activity
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006808	biological_process	regulation of nitrogen utilization
J	0030234	molecular_function	enzyme regulator activity
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006808	biological_process	regulation of nitrogen utilization
K	0030234	molecular_function	enzyme regulator activity
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006808	biological_process	regulation of nitrogen utilization
L	0030234	molecular_function	enzyme regulator activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT A1116

Chain	Residue
A	LYS3
A	GLU5
B	LYS3
B	GLU5
C	LYS3
C	GLU5
C	ILE94

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACT A1117

Chain	Residue
A	GLY87
A	ASP88
A	HOH2043
A	HOH2057
C	ARG101
C	ARG103
A	ASN85
A	PRO86

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACT E1116

Chain	Residue
D	LYS3
D	GLU5
D	ILE94
E	LYS3
E	GLU5
F	LYS3
F	GLU5
F	ILE94

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT H1113

Chain	Residue
G	LYS3
G	GLU5
G	ILE94
H	LYS3
H	GLU5
I	LYS3
I	GLU5

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL J1114

Chain	Residue
J	LYS60

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT J1116

Chain	Residue
J	LYS3
J	GLU5
K	LYS3
K	GLU5
L	LYS3
L	GLU5

---

site_id	AC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE ADP B1115

Chain	Residue
B	GLY27
B	MET28
B	THR29
B	GLU62
B	LEU63
B	VAL64
B	ARG101
B	ARG103
B	HOH2077
B	HOH2078
C	ILE7
C	GLY35
C	ARG36
C	GLY37
C	VAL38
C	LYS58
C	GLY87
C	ASP88
C	GLY89
C	LYS90

---

site_id	AC8
Number of Residues	16
Details	BINDING SITE FOR RESIDUE AMP E1115

Chain	Residue
E	GLY27
E	MET28
E	THR29
E	GLU62
E	LEU63
E	VAL64
E	ARG101
E	GLU114
F	ILE7
F	GLY35
F	VAL38
F	LYS58
F	GLY87
F	ASP88
F	GLY89
F	LYS90

---

site_id	AC9
Number of Residues	20
Details	BINDING SITE FOR RESIDUE ADP I1115

Chain	Residue
H	GLY27
H	THR29
H	GLU62
H	LEU63
H	VAL64
H	ARG101
H	ARG103
I	ILE7
I	GLY35
I	ARG36
I	LYS58
I	ASN85
I	PRO86
I	GLY87
I	ASP88
I	GLY89
I	LYS90
I	PHE92
I	HOH2040
I	HOH2041

---

site_id	BC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE ADP J1115

Chain	Residue
J	PRO86
J	GLY87
J	ASP88
J	GLY89
J	LYS90
J	HOH2043
J	HOH2044
L	GLY27
L	THR29
L	GLU62
L	LEU63
L	VAL64
L	ARG101
L	ARG103
J	ILE7
J	GLY35
J	ARG36
J	GLY37
J	VAL38
J	LYS58

---

site_id	BC2
Number of Residues	22
Details	BINDING SITE FOR RESIDUE ADP L1114

Chain	Residue
K	GLY27
K	MET28
K	THR29
K	GLU62
K	LEU63
K	VAL64
K	ARG101
K	ARG103
K	GLU114
L	ILE7
L	GLY35
L	ARG36
L	GLY37
L	VAL38
L	GLN39
L	LYS58
L	GLY87
L	ASP88
L	GLY89
L	LYS90
L	HOH2072
L	HOH2073

---

Functional Information from PROSITE/UniProt

site_id	PS00638
Number of Residues	14
Details	PII_GLNB_CTER P-II protein C-terminal region signature. TgnpGDGKIFVipV

Chain	Residue	Details
A	THR83-VAL96
E	THR83-VAL96

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	107
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17203075","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J9C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2J9E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17203075","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2J9D","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17203075","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---