2J7H
Beta-glucosidase from Thermotoga maritima in complex with azafagomine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000272 | biological_process | polysaccharide catabolic process |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008422 | molecular_function | beta-glucosidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030245 | biological_process | cellulose catabolic process |
| B | 0000272 | biological_process | polysaccharide catabolic process |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0008422 | molecular_function | beta-glucosidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030245 | biological_process | cellulose catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A1447 |
| Chain | Residue |
| A | HIS40 |
| A | ASP52 |
| A | ACT1448 |
| A | HOH2055 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A1448 |
| Chain | Residue |
| A | HIS40 |
| A | ASP52 |
| A | CA1447 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A1449 |
| Chain | Residue |
| A | TYR421 |
| A | HOH2027 |
| A | VAL53 |
| A | ALA54 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B1446 |
| Chain | Residue |
| B | HIS40 |
| B | ASP52 |
| B | ACT1448 |
| B | HOH2022 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B1447 |
| Chain | Residue |
| B | ASP278 |
| B | SER281 |
| B | GLU282 |
| B | HOH2161 |
| B | HOH2167 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B1448 |
| Chain | Residue |
| B | HIS36 |
| B | HIS40 |
| B | ASP52 |
| B | CA1446 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE AZF A1446 |
| Chain | Residue |
| A | GLN20 |
| A | HIS121 |
| A | GLU166 |
| A | TYR295 |
| A | TRP324 |
| A | GLU351 |
| A | TRP398 |
| A | GLU405 |
| A | TRP406 |
| A | PHE414 |
| A | HOH2186 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AZF B1445 |
| Chain | Residue |
| B | GLN20 |
| B | HIS121 |
| B | GLU166 |
| B | TYR295 |
| B | TRP324 |
| B | GLU351 |
| B | TRP398 |
| B | GLU405 |
| B | TRP406 |
| B | HOH2094 |
Functional Information from PROSITE/UniProt
| site_id | PS00572 |
| Number of Residues | 9 |
| Details | GLYCOSYL_HYDROL_F1_1 Glycosyl hydrolases family 1 active site. VYITENGAA |
| Chain | Residue | Details |
| A | VAL347-ALA355 |
| site_id | PS00653 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F1_2 Glycosyl hydrolases family 1 N-terminal signature. FlWGvAtASYQiEgS |
| Chain | Residue | Details |
| A | PHE10-SER24 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU10055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1cbg |
| Chain | Residue | Details |
| A | GLU166 | |
| A | ASN293 | |
| A | GLU351 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1cbg |
| Chain | Residue | Details |
| B | GLU166 | |
| B | ASN293 | |
| B | GLU351 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1cbg |
| Chain | Residue | Details |
| A | GLU166 | |
| A | GLU351 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1cbg |
| Chain | Residue | Details |
| B | GLU166 | |
| B | GLU351 |
