2J7B
Beta-glucosidase from Thermotoga maritima in complex with gluco- tetrazole
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008422 | molecular_function | beta-glucosidase activity |
| A | 0016052 | biological_process | carbohydrate catabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030245 | biological_process | cellulose catabolic process |
| A | 0102483 | molecular_function | scopolin beta-glucosidase activity |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0008422 | molecular_function | beta-glucosidase activity |
| B | 0016052 | biological_process | carbohydrate catabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030245 | biological_process | cellulose catabolic process |
| B | 0102483 | molecular_function | scopolin beta-glucosidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A1447 |
| Chain | Residue |
| A | VAL53 |
| A | ALA54 |
| A | TYR410 |
| A | TYR421 |
| A | GLN424 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT B1447 |
| Chain | Residue |
| B | TYR177 |
| B | PHE267 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CA B1448 |
| Chain | Residue |
| B | ASP278 |
| B | SER281 |
| B | GLU282 |
| B | HOH2221 |
| B | HOH2222 |
| B | HOH2226 |
| A | HOH2158 |
| A | HOH2159 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE NTZ A1446 |
| Chain | Residue |
| A | GLN20 |
| A | HIS121 |
| A | ASN165 |
| A | GLU166 |
| A | TYR295 |
| A | TRP324 |
| A | GLU351 |
| A | TRP398 |
| A | GLU405 |
| A | TRP406 |
| A | PHE414 |
| A | HOH2431 |
| A | HOH2432 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE NTZ B1446 |
| Chain | Residue |
| B | GLN20 |
| B | HIS121 |
| B | ASN165 |
| B | GLU166 |
| B | TYR295 |
| B | TRP324 |
| B | GLU351 |
| B | TRP398 |
| B | GLU405 |
| B | TRP406 |
| B | PHE414 |
| B | HOH2134 |
| B | HOH2304 |
| B | HOH2305 |
Functional Information from PROSITE/UniProt
| site_id | PS00572 |
| Number of Residues | 9 |
| Details | GLYCOSYL_HYDROL_F1_1 Glycosyl hydrolases family 1 active site. VYITENGAA |
| Chain | Residue | Details |
| A | VAL347-ALA355 |
| site_id | PS00653 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F1_2 Glycosyl hydrolases family 1 N-terminal signature. FlWGvAtASYQiEgS |
| Chain | Residue | Details |
| A | PHE10-SER24 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000255 |
| Chain | Residue | Details |
| A | GLU166 | |
| B | GLU166 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU10055 |
| Chain | Residue | Details |
| A | GLU351 | |
| B | GLU351 |
