Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2J63

Crystal structure of AP endonuclease LMAP from Leishmania major

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003824molecular_functioncatalytic activity
A0003906molecular_functionDNA-(apurinic or apyrimidinic site) endonuclease activity
A0004518molecular_functionnuclease activity
A0004519molecular_functionendonuclease activity
A0005634cellular_componentnucleus
A0006281biological_processDNA repair
A0006284biological_processbase-excision repair
A0008081molecular_functionphosphoric diester hydrolase activity
A0008311molecular_functiondouble-stranded DNA 3'-5' DNA exonuclease activity
A0016829molecular_functionlyase activity
A0046872molecular_functionmetal ion binding
B0003677molecular_functionDNA binding
B0003824molecular_functioncatalytic activity
B0003906molecular_functionDNA-(apurinic or apyrimidinic site) endonuclease activity
B0004518molecular_functionnuclease activity
B0004519molecular_functionendonuclease activity
B0005634cellular_componentnucleus
B0006281biological_processDNA repair
B0006284biological_processbase-excision repair
B0008081molecular_functionphosphoric diester hydrolase activity
B0008311molecular_functiondouble-stranded DNA 3'-5' DNA exonuclease activity
B0016829molecular_functionlyase activity
B0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS00726
Number of Residues10
DetailsAP_NUCLEASE_F1_1 AP endonucleases family 1 signature 1. PDVLCLQETK
ChainResidueDetails
APRO160-LYS169

site_idPS00728
Number of Residues12
DetailsAP_NUCLEASE_F1_3 AP endonucleases family 1 signature 3. NlGwRLDYfVvS
ChainResidueDetails
AASN405-SER416

Catalytic Information from CSA
site_idCSA1
Number of Residues5
DetailsAnnotated By Reference To The Literature 1ako
ChainResidueDetails
AASN136
AASN337
AASP335
AASP411
AHIS437

site_idCSA2
Number of Residues5
DetailsAnnotated By Reference To The Literature 1ako
ChainResidueDetails
BASN136
BASN337
BASP335
BASP411
BHIS437

227111

PDB entries from 2024-11-06

PDB statisticsPDBj update infoContact PDBjnumon