2J55

X-ray reduced Paraccocus denitrificans methylamine dehydrogenase O- quinone in complex with amicyanin.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0009055	molecular_function	electron transfer activity
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
B	0005507	molecular_function	copper ion binding
B	0009055	molecular_function	electron transfer activity
B	0042597	cellular_component	periplasmic space
B	0046872	molecular_function	metal ion binding
H	0016491	molecular_function	oxidoreductase activity
H	0030058	molecular_function	amine dehydrogenase activity
H	0030416	biological_process	methylamine metabolic process
H	0042597	cellular_component	periplasmic space
H	0052876	molecular_function	methylamine dehydrogenase (amicyanin) activity
J	0016491	molecular_function	oxidoreductase activity
J	0030058	molecular_function	amine dehydrogenase activity
J	0030416	biological_process	methylamine metabolic process
J	0042597	cellular_component	periplasmic space
J	0052876	molecular_function	methylamine dehydrogenase (amicyanin) activity
L	0009308	biological_process	amine metabolic process
L	0016491	molecular_function	oxidoreductase activity
L	0016638	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors
L	0030288	cellular_component	outer membrane-bounded periplasmic space
L	0042597	cellular_component	periplasmic space
L	0052876	molecular_function	methylamine dehydrogenase (amicyanin) activity
M	0009308	biological_process	amine metabolic process
M	0016491	molecular_function	oxidoreductase activity
M	0016638	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors
M	0030288	cellular_component	outer membrane-bounded periplasmic space
M	0042597	cellular_component	periplasmic space
M	0052876	molecular_function	methylamine dehydrogenase (amicyanin) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU A 1106

Chain	Residue
A	HIS53
A	CYS92
A	HIS95
A	MET98

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU B 1106

Chain	Residue
B	HIS53
B	CYS92
B	HIS95
B	MET98

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL H 1387

Chain	Residue
H	HIS250
H	LEU262
H	ALA264
H	HOH2277
H	PHE220

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL H 1388

Chain	Residue
H	HIS54
H	TRP282
H	GLN378
H	HOH2392
H	HOH2402
L	HOH2021

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL H 1389

Chain	Residue
H	GLN14
H	ALA18
H	ARG70
H	HOH2012
H	HOH2403
H	HOH2405
H	HOH2406
M	ASP37

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL L 1132

Chain	Residue
H	ARG305
L	CYS23
L	CYS88
L	LEU89
L	ASN90
L	HOH2048
L	HOH2073
L	HOH2074
L	HOH2075

---

Functional Information from PROSITE/UniProt

site_id	PS00196
Number of Residues	14
Details	COPPER_BLUE Type-1 copper (blue) proteins signature. AgtYdYHCt.P.Hpf..M

Chain	Residue	Details
A	ALA85-MET98

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Tryptophylquinone => ECO:0000269|PubMed:1409575

Chain	Residue	Details
L	TRQ57
M	TRQ57
A	HIS95
A	MET98
B	HIS53
B	CYS92
B	HIS95
B	MET98

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	CROSSLNK: Tryptophan tryptophylquinone (Trp-Trp) => ECO:0000269|PubMed:1409575

Chain	Residue	Details
L	TRQ57
L	TRP108
M	TRQ57
M	TRP108

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	5
Details	Annotated By Reference To The Literature 2bbk

Chain	Residue	Details
L	ASP76
L	THR122
L	ASP32
L	TYR119
L	TRP108

---

site_id	CSA2
Number of Residues	5
Details	Annotated By Reference To The Literature 2bbk

Chain	Residue	Details
M	ASP76
M	THR122
M	ASP32
M	TYR119
M	TRP108

---

site_id	MCSA1
Number of Residues	6
Details	M-CSA 13

Chain	Residue	Details
L	ASP32	electrostatic stabiliser, proton acceptor, proton donor
L	TRQ57	proton acceptor, proton donor, proton relay
L	ASP76	electrostatic stabiliser, proton acceptor, proton donor
L	TRP108	proton acceptor, proton donor, proton relay, single electron donor
L	TYR119	steric role
L	THR122	electrostatic stabiliser

---

site_id	MCSA2
Number of Residues	6
Details	M-CSA 13

Chain	Residue	Details
M	ASP32	electrostatic stabiliser, proton acceptor, proton donor
M	TRQ57	proton acceptor, proton donor, proton relay
M	ASP76	electrostatic stabiliser, proton acceptor, proton donor
M	TRP108	proton acceptor, proton donor, proton relay, single electron donor
M	TYR119	steric role
M	THR122	electrostatic stabiliser

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