2J3M
PROLYL-TRNA SYNTHETASE FROM ENTEROCOCCUS FAECALIS COMPLEXED WITH ATP, manganese and prolinol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002161 | molecular_function | aminoacyl-tRNA deacylase activity |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004827 | molecular_function | proline-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006433 | biological_process | prolyl-tRNA aminoacylation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016874 | molecular_function | ligase activity |
| A | 0106074 | biological_process | aminoacyl-tRNA metabolism involved in translational fidelity |
| A | 0140096 | molecular_function | catalytic activity, acting on a protein |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0002161 | molecular_function | aminoacyl-tRNA deacylase activity |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004827 | molecular_function | proline-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006433 | biological_process | prolyl-tRNA aminoacylation |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016874 | molecular_function | ligase activity |
| B | 0106074 | biological_process | aminoacyl-tRNA metabolism involved in translational fidelity |
| B | 0140096 | molecular_function | catalytic activity, acting on a protein |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A1567 |
| Chain | Residue |
| A | GLU407 |
| A | HIS410 |
| A | ATP701 |
| A | MN1568 |
| A | HOH2200 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A1568 |
| Chain | Residue |
| A | GLU407 |
| A | ATP701 |
| A | MN1567 |
| A | HOH2201 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B1567 |
| Chain | Residue |
| B | GLU407 |
| B | HIS410 |
| B | ATP701 |
| B | MN1568 |
| B | HOH2157 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B1568 |
| Chain | Residue |
| B | GLU209 |
| B | GLU407 |
| B | ATP701 |
| B | MN1567 |
| B | HOH2158 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MN B1569 |
| Chain | Residue |
| B | ATP701 |
| B | HOH2159 |
| B | HOH2160 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MN B1570 |
| Chain | Residue |
| A | ATP701 |
| B | HOH2161 |
| B | HOH2162 |
| site_id | AC7 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ATP A 701 |
| Chain | Residue |
| A | ARG140 |
| A | GLU142 |
| A | LEU150 |
| A | ARG151 |
| A | GLY152 |
| A | PHE155 |
| A | MET157 |
| A | GLU407 |
| A | ILE408 |
| A | GLY409 |
| A | HIS410 |
| A | GLY444 |
| A | ARG447 |
| A | PRI1566 |
| A | MN1567 |
| A | MN1568 |
| A | HOH2064 |
| A | HOH2084 |
| A | HOH2199 |
| A | HOH2200 |
| A | HOH2201 |
| B | MN1570 |
| B | HOH2162 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PRI A1566 |
| Chain | Residue |
| A | THR109 |
| A | GLU111 |
| A | ARG140 |
| A | MET157 |
| A | TYR161 |
| A | PHE412 |
| A | CYS440 |
| A | TYR441 |
| A | GLY442 |
| A | ATP701 |
| A | HOH2030 |
| site_id | AC9 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ATP B 701 |
| Chain | Residue |
| B | ARG140 |
| B | GLU142 |
| B | ARG151 |
| B | GLY152 |
| B | PHE155 |
| B | MET157 |
| B | GLU407 |
| B | ILE408 |
| B | GLY409 |
| B | HIS410 |
| B | GLY444 |
| B | ARG447 |
| B | PRI1566 |
| B | MN1567 |
| B | MN1568 |
| B | MN1569 |
| B | HOH2066 |
| B | HOH2087 |
| B | HOH2088 |
| B | HOH2154 |
| B | HOH2157 |
| B | HOH2158 |
| B | HOH2160 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PRI B1566 |
| Chain | Residue |
| B | THR109 |
| B | GLU111 |
| B | ARG140 |
| B | MET157 |
| B | ASP159 |
| B | TYR161 |
| B | CYS440 |
| B | TYR441 |
| B | GLY442 |
| B | ATP701 |
| B | HOH2033 |
| B | HOH2156 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qf6 |
| Chain | Residue | Details |
| A | ARG140 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qf6 |
| Chain | Residue | Details |
| B | ARG140 |
