2J1N

osmoporin OmpC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001618	molecular_function	virus receptor activity
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0006974	biological_process	DNA damage response
A	0009279	cellular_component	cell outer membrane
A	0015288	molecular_function	porin activity
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0046718	biological_process	symbiont entry into host cell
A	0046813	biological_process	receptor-mediated virion attachment to host cell
A	0046872	molecular_function	metal ion binding
A	0046930	cellular_component	pore complex
A	0120010	biological_process	intermembrane phospholipid transfer
B	0001618	molecular_function	virus receptor activity
B	0005515	molecular_function	protein binding
B	0006811	biological_process	monoatomic ion transport
B	0006974	biological_process	DNA damage response
B	0009279	cellular_component	cell outer membrane
B	0015288	molecular_function	porin activity
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0046718	biological_process	symbiont entry into host cell
B	0046813	biological_process	receptor-mediated virion attachment to host cell
B	0046872	molecular_function	metal ion binding
B	0046930	cellular_component	pore complex
B	0120010	biological_process	intermembrane phospholipid transfer
C	0001618	molecular_function	virus receptor activity
C	0005515	molecular_function	protein binding
C	0006811	biological_process	monoatomic ion transport
C	0006974	biological_process	DNA damage response
C	0009279	cellular_component	cell outer membrane
C	0015288	molecular_function	porin activity
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0046718	biological_process	symbiont entry into host cell
C	0046813	biological_process	receptor-mediated virion attachment to host cell
C	0046872	molecular_function	metal ion binding
C	0046930	cellular_component	pore complex
C	0120010	biological_process	intermembrane phospholipid transfer

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A1347

Chain	Residue
A	ASN319
A	LEU321
A	THR334
A	HOH2140
A	HOH2148

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B1347

Chain	Residue
B	HOH2194
B	ASN319
B	LEU321
B	THR334
B	HOH2191

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B1348

Chain	Residue
B	THR47
B	ASP48
C	THR47
C	ASP48

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B1349

Chain	Residue
A	ASN69
B	ASN69
C	ASN69

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C1347

Chain	Residue
C	ASN319
C	LEU321
C	THR334
C	HOH2189
C	HOH2191
C	HOH2202

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE D12 C1348

Chain	Residue
B	VAL338
C	TYR277
C	GLN279
C	D121350

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE D12 C1349

Chain	Residue
A	TYR131
C	GLY194
C	GLY223
C	GLY224

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE D12 C1350

Chain	Residue
B	LEU340
C	PHE259
C	D121348

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE D12 C1351

Chain	Residue
A	TYR149
C	ILE197
C	THR222

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE D12 C1352

Chain	Residue
C	LYS226
C	TYR227
C	VAL262
C	ALA276
C	TYR277

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE D12 C1353

Chain	Residue
C	TYR94
C	HOH2027

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE D12 C1354

Chain	Residue
C	PHE23
C	ASN336
C	ILE337
C	VAL338

---

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE D12 C1357

Chain	Residue
A	ARG132

---

Functional Information from PROSITE/UniProt

site_id	PS00576
Number of Residues	17
Details	GRAM_NEG_PORIN General diffusion Gram-negative porins signature. VdvGatYyFnKnmSTYV

Chain	Residue	Details
A	VAL298-VAL314

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	138
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"16949612","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	399
Details	Transmembrane: {"description":"Beta stranded"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	405
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"16949612","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	51
Details	Region: {"description":"Loop L3; may constrict the pore"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PDB","id":"2J1N","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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