2IZO
Structure of an Archaeal PCNA1-PCNA2-FEN1 Complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008409 | molecular_function | 5'-3' exonuclease activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| A | 0017108 | molecular_function | 5'-flap endonuclease activity |
| A | 0043137 | biological_process | DNA replication, removal of RNA primer |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0006260 | biological_process | DNA replication |
| B | 0006272 | biological_process | leading strand elongation |
| B | 0006275 | biological_process | regulation of DNA replication |
| B | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0006260 | biological_process | DNA replication |
| C | 0006272 | biological_process | leading strand elongation |
| C | 0006275 | biological_process | regulation of DNA replication |
| C | 0030337 | molecular_function | DNA polymerase processivity factor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN A1347 |
| Chain | Residue |
| A | ASP170 |
| A | HOH2014 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A1348 |
| Chain | Residue |
| A | ASP237 |
| B | GLU146 |
| B | ASP149 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B1246 |
| Chain | Residue |
| B | GLU61 |
| B | LYS159 |
| B | GLU160 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B1247 |
| Chain | Residue |
| C | GLU162 |
| C | HOH2017 |
| C | HOH2018 |
| B | GLU234 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C1250 |
| Chain | Residue |
| C | THR23 |
| C | SER25 |
| C | ILE27 |
| C | HIS39 |
| C | HOH2006 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN C1251 |
| Chain | Residue |
| C | GLU203 |
| C | LYS206 |
| C | ASP207 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN C1252 |
| Chain | Residue |
| C | GLU234 |
| C | HIS240 |
| C | HOH2029 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Region: {"description":"Interaction with PCNA"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00614","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
