2IZO

Structure of an Archaeal PCNA1-PCNA2-FEN1 Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003824	molecular_function	catalytic activity
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity
A	0004527	molecular_function	exonuclease activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0008409	molecular_function	5'-3' exonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0017108	molecular_function	5'-flap endonuclease activity
A	0030145	molecular_function	manganese ion binding
A	0043137	biological_process	DNA replication, removal of RNA primer
A	0046872	molecular_function	metal ion binding
B	0003677	molecular_function	DNA binding
B	0006260	biological_process	DNA replication
B	0006272	biological_process	leading strand elongation
B	0006275	biological_process	regulation of DNA replication
B	0006298	biological_process	mismatch repair
B	0019985	biological_process	translesion synthesis
B	0030337	molecular_function	DNA polymerase processivity factor activity
C	0003677	molecular_function	DNA binding
C	0006260	biological_process	DNA replication
C	0006272	biological_process	leading strand elongation
C	0006275	biological_process	regulation of DNA replication
C	0006298	biological_process	mismatch repair
C	0019985	biological_process	translesion synthesis
C	0030337	molecular_function	DNA polymerase processivity factor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A1347

Chain	Residue
A	ASP170
A	HOH2014

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A1348

Chain	Residue
A	ASP237
B	GLU146
B	ASP149

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN B1246

Chain	Residue
B	GLU61
B	LYS159
B	GLU160

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B1247

Chain	Residue
C	GLU162
C	HOH2017
C	HOH2018
B	GLU234

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C1250

Chain	Residue
C	THR23
C	SER25
C	ILE27
C	HIS39
C	HOH2006

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN C1251

Chain	Residue
C	GLU203
C	LYS206
C	ASP207

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN C1252

Chain	Residue
C	GLU234
C	HIS240
C	HOH2029

---

Functional Information from PROSITE/UniProt

site_id	PS00841
Number of Residues	15
Details	XPG_1 XPG protein signature 1. VIPiYVFDGkpPeQK

Chain	Residue	Details
A	VAL70-LYS84

---

site_id	PS01251
Number of Residues	24
Details	PCNA_1 Proliferating cell nuclear antigen signature 1. GIrVsGIDpSRVvFLdIfLpssyF

Chain	Residue	Details
B	GLY34-PHE57

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00614

Chain	Residue	Details
A	ASP24
A	ASP77
A	GLU149
A	GLU151
A	ASP170
A	ASP172
A	ASP233

---