2IX9
Respective role of protein folding and glycosylation in the thermal stability of recombinant Feruloyl Esterase A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000272 | biological_process | polysaccharide catabolic process |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0030245 | biological_process | cellulose catabolic process |
| A | 0030248 | molecular_function | cellulose binding |
| A | 0030600 | molecular_function | feruloyl esterase activity |
| A | 0044347 | biological_process | cell wall polysaccharide catabolic process |
| A | 0045490 | biological_process | pectin catabolic process |
| A | 0045493 | biological_process | xylan catabolic process |
| A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| B | 0000272 | biological_process | polysaccharide catabolic process |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0030245 | biological_process | cellulose catabolic process |
| B | 0030248 | molecular_function | cellulose binding |
| B | 0030600 | molecular_function | feruloyl esterase activity |
| B | 0044347 | biological_process | cell wall polysaccharide catabolic process |
| B | 0045490 | biological_process | pectin catabolic process |
| B | 0045493 | biological_process | xylan catabolic process |
| B | 0052689 | molecular_function | carboxylic ester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1267 |
| Chain | Residue |
| A | ARG162 |
| A | ALA207 |
| A | HIS208 |
| A | HOH2281 |
| A | HOH2282 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B1265 |
| Chain | Residue |
| B | ARG162 |
| B | ALA207 |
| B | HIS208 |
| B | HOH2243 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CXS A1261 |
| Chain | Residue |
| A | TYR25 |
| A | THR68 |
| A | SER133 |
| A | HIS247 |
| A | SER255 |
| A | GLY256 |
| A | EDO1265 |
| A | HOH2271 |
| A | HOH2272 |
| A | HOH2273 |
| A | HOH2274 |
| B | ASP71 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A1262 |
| Chain | Residue |
| A | ASP77 |
| A | TYR80 |
| A | HIS97 |
| A | TYR100 |
| A | LEU199 |
| A | EDO1264 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A1263 |
| Chain | Residue |
| A | GLU160 |
| A | SER163 |
| A | GLY164 |
| A | PHE168 |
| A | ALA169 |
| A | MET172 |
| A | TYR186 |
| A | ALA207 |
| A | GLY209 |
| A | HOH2276 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A1264 |
| Chain | Residue |
| A | ASP77 |
| A | TYR100 |
| A | SER133 |
| A | EDO1262 |
| A | HOH2277 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A1265 |
| Chain | Residue |
| A | THR248 |
| A | THR254 |
| A | SER255 |
| A | CXS1261 |
| A | HOH2266 |
| A | HOH2278 |
| B | GLN45 |
| B | ASP71 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A1266 |
| Chain | Residue |
| A | SER7 |
| A | GLU8 |
| A | ASP9 |
| A | HOH2279 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CXS B1261 |
| Chain | Residue |
| A | ASP71 |
| A | LEU74 |
| A | HOH2102 |
| B | TYR25 |
| B | THR68 |
| B | HIS247 |
| B | SER255 |
| B | GLY256 |
| B | HOH2240 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B1262 |
| Chain | Residue |
| B | ASP77 |
| B | TYR80 |
| B | HIS97 |
| B | TYR100 |
| B | EDO1264 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B1263 |
| Chain | Residue |
| B | GLU160 |
| B | SER163 |
| B | GLY164 |
| B | PHE168 |
| B | TYR186 |
| B | ALA207 |
| B | GLY209 |
| B | HOH2241 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B1264 |
| Chain | Residue |
| B | LEU74 |
| B | ASP77 |
| B | VAL243 |
| B | EDO1262 |
| B | HOH2242 |
Functional Information from PROSITE/UniProt
| site_id | PS00120 |
| Number of Residues | 10 |
| Details | LIPASE_SER Lipases, serine active site. LTVTGHSLGA |
| Chain | Residue | Details |
| A | LEU127-ALA136 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"15081808","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"15103133","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16128806","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"17027758","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
