2IW0

Structure of the chitin deacetylase from the fungal pathogen Colletotrichum lindemuthianum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005975	biological_process	carbohydrate metabolic process
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A1255

Chain	Residue
A	ASP50
A	HIS104
A	HIS108
A	ACT1256
A	HOH2173

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ACT A1256

Chain	Residue
A	PRO144
A	TYR145
A	HIS206
A	HIS254
A	ZN1255
A	HOH2173
A	ASP49
A	ASP50
A	HIS104
A	HIS108

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A1257

Chain	Residue
A	ASP110
A	ASN112
A	ARG132
A	ILE133
A	SER147
A	HOH2085

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT A1258

Chain	Residue
A	ARG93
A	GLU210
A	HOH2174

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A1259

Chain	Residue
A	ARG124
A	HIS254
A	HOH2132

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 A1260

Chain	Residue
A	ARG124
A	ARG131
A	LYS247
A	HIS249
A	HIS250
A	HIS251
A	HIS254
A	HOH2175

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	190
Details	Domain: {"description":"NodB homology","evidences":[{"source":"PROSITE-ProRule","id":"PRU01014","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"16878976","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"16878976","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16878976","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2IW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16878976","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2IW0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Site: {"description":"Prevents de-N-acetylated sugar residues from interacting with the active site","evidences":[{"source":"PubMed","id":"16878976","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

---