Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2IVO

Structure of UP1 protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000408	cellular_component	EKC/KEOPS complex
A	0002949	biological_process	tRNA threonylcarbamoyladenosine modification
A	0003727	molecular_function	single-stranded RNA binding
A	0005506	molecular_function	iron ion binding
A	0005737	cellular_component	cytoplasm
A	0006400	biological_process	tRNA modification
A	0008033	biological_process	tRNA processing
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0046872	molecular_function	metal ion binding
A	0061711	molecular_function	tRNA N(6)-L-threonylcarbamoyladenine synthase activity
A	0070525	biological_process	tRNA threonylcarbamoyladenosine metabolic process
B	0000049	molecular_function	tRNA binding
B	0000408	cellular_component	EKC/KEOPS complex
B	0002949	biological_process	tRNA threonylcarbamoyladenosine modification
B	0003727	molecular_function	single-stranded RNA binding
B	0005506	molecular_function	iron ion binding
B	0005737	cellular_component	cytoplasm
B	0006400	biological_process	tRNA modification
B	0008033	biological_process	tRNA processing
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0046872	molecular_function	metal ion binding
B	0061711	molecular_function	tRNA N(6)-L-threonylcarbamoyladenine synthase activity
B	0070525	biological_process	tRNA threonylcarbamoyladenosine metabolic process
C	0000049	molecular_function	tRNA binding
C	0000408	cellular_component	EKC/KEOPS complex
C	0002949	biological_process	tRNA threonylcarbamoyladenosine modification
C	0003727	molecular_function	single-stranded RNA binding
C	0005506	molecular_function	iron ion binding
C	0005737	cellular_component	cytoplasm
C	0006400	biological_process	tRNA modification
C	0008033	biological_process	tRNA processing
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0046872	molecular_function	metal ion binding
C	0061711	molecular_function	tRNA N(6)-L-threonylcarbamoyladenine synthase activity
C	0070525	biological_process	tRNA threonylcarbamoyladenosine metabolic process
D	0000049	molecular_function	tRNA binding
D	0000408	cellular_component	EKC/KEOPS complex
D	0002949	biological_process	tRNA threonylcarbamoyladenosine modification
D	0003727	molecular_function	single-stranded RNA binding
D	0005506	molecular_function	iron ion binding
D	0005737	cellular_component	cytoplasm
D	0006400	biological_process	tRNA modification
D	0008033	biological_process	tRNA processing
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0046872	molecular_function	metal ion binding
D	0061711	molecular_function	tRNA N(6)-L-threonylcarbamoyladenine synthase activity
D	0070525	biological_process	tRNA threonylcarbamoyladenosine metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE WO4 A1326

Chain	Residue
A	GLY81
A	PRO82
A	ARG85
A	GLN313

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE WO4 A1327

Chain	Residue
A	ARG208

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE WO4 B1326

Chain	Residue
B	GLY81
B	PRO82
B	ARG85
B	GLN313

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE WO4 C1326

Chain	Residue
C	GLY81
C	PRO82
C	ARG85
C	GLN313

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE WO4 C1327

Chain	Residue
C	ARG208

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE WO4 D1326

Chain	Residue
D	GLY81
D	ARG85
D	GLN313

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE WO4 A1328

Chain	Residue
A	ARG85
A	ARG92
A	THR309
A	ILE310
A	VAL311
D	ARG99

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE WO4 C1328

Chain	Residue
B	ARG99
C	ARG85
C	ARG92
C	ILE310
C	VAL311

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE WO4 A1329

Chain	Residue
A	ARG305
D	ARG305

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE WO4 B1327

Chain	Residue
B	ARG305
C	ARG305

Functional Information from PROSITE/UniProt

site_id	PS01016
Number of Residues	21
Details	GLYCOPROTEASE Glycoprotease family signature. RAlavkYRkPiVgvnHciAHV

Chain	Residue	Details
A	ARG92-VAL112

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01446","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17766251","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	32
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)