2IVE
Structure of protoporphyrinogen oxidase from Myxococcus xanthus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004729 | molecular_function | oxygen-dependent protoporphyrinogen oxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| A | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| A | 0006783 | biological_process | heme biosynthetic process |
| A | 0016117 | biological_process | carotenoid biosynthetic process |
| A | 0016166 | molecular_function | phytoene dehydrogenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0004729 | molecular_function | oxygen-dependent protoporphyrinogen oxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| B | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| B | 0006783 | biological_process | heme biosynthetic process |
| B | 0016117 | biological_process | carotenoid biosynthetic process |
| B | 0016166 | molecular_function | phytoene dehydrogenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE FAD A2114 |
| Chain | Residue |
| A | VAL15 |
| A | GLY46 |
| A | ALA47 |
| A | GLY61 |
| A | PRO62 |
| A | ASN63 |
| A | SER64 |
| A | ALA249 |
| A | VAL251 |
| A | ALA282 |
| A | ALA287 |
| A | GLY16 |
| A | GLY440 |
| A | ASN441 |
| A | VAL446 |
| A | GLY447 |
| A | LEU448 |
| A | HOH2003 |
| A | HOH2072 |
| A | TWN4002 |
| A | GLY18 |
| A | ILE19 |
| A | SER20 |
| A | LEU38 |
| A | GLU39 |
| A | SER40 |
| A | SER41 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TWN A4002 |
| Chain | Residue |
| A | THR166 |
| A | GLY167 |
| A | ILE168 |
| A | ALA170 |
| A | ILE311 |
| A | PHE329 |
| A | GLY330 |
| A | PHE331 |
| A | LEU332 |
| A | GLY343 |
| A | ALA344 |
| A | ILE345 |
| A | MET365 |
| A | FAD2114 |
| site_id | AC3 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE FAD B2114 |
| Chain | Residue |
| B | VAL15 |
| B | GLY16 |
| B | GLY18 |
| B | ILE19 |
| B | SER20 |
| B | LEU38 |
| B | GLU39 |
| B | SER40 |
| B | GLY46 |
| B | ALA47 |
| B | GLY61 |
| B | PRO62 |
| B | ASN63 |
| B | SER64 |
| B | VAL251 |
| B | ALA282 |
| B | ALA283 |
| B | PRO284 |
| B | ALA287 |
| B | GLY440 |
| B | ASN441 |
| B | GLY447 |
| B | LEU448 |
| B | HOH2068 |
| B | HOH2069 |
| B | HOH2070 |
| B | TWN4003 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE TWN B4001 |
| Chain | Residue |
| B | LEU125 |
| B | ARG126 |
| B | GLY129 |
| B | ARG134 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE TWN B4003 |
| Chain | Residue |
| B | THR166 |
| B | GLY167 |
| B | ILE168 |
| B | PHE329 |
| B | GLY330 |
| B | PHE331 |
| B | LEU332 |
| B | ALA344 |
| B | ILE345 |
| B | MET365 |
| B | FAD2114 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A3001 |
| Chain | Residue |
| A | PRO120 |
| A | LEU121 |
| A | GLY122 |
| A | ALA123 |
| A | ARG201 |
| A | HOH2073 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A3002 |
| Chain | Residue |
| A | GLY122 |
| A | ALA123 |
| A | ARG193 |
| A | LEU197 |
| A | ARG201 |
| A | HOH2026 |
| A | HOH2043 |
| A | HOH2074 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A3003 |
| Chain | Residue |
| A | ARG126 |
| A | GLY129 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B3005 |
| Chain | Residue |
| B | PRO120 |
| B | GLY122 |
| B | ARG201 |
| B | HOH2071 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B3006 |
| Chain | Residue |
| A | LEU125 |
| B | LEU125 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B3007 |
| Chain | Residue |
| B | GLY122 |
| B | ALA123 |
| B | ARG193 |
| B | LEU197 |
| B | ARG201 |
| B | HOH2032 |
| B | HOH2072 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17046834 |
| Chain | Residue | Details |
| B | ALA47 | |
| B | GLY61 | |
| B | VAL251 | |
| B | VAL446 | |
| A | GLY16 | |
| A | GLU39 | |
| A | ALA47 | |
| A | GLY61 | |
| A | VAL251 | |
| A | VAL446 | |
| B | GLY16 | |
| B | GLU39 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | TRP408 | |
| B | TRP408 |
